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Jul 5, 2014 · In Messina, Mechnikov formed his theory of phagocytosis from observation of the moving cells surrounding foreign material in transparent starfish larvae. Mechnikov noted that the process was similar to the inflammatory response found in animals with vascular systems.
At Messina he discovered phagocytosis after experimenting on the larvae of starfish. In 1882 he first demonstrated the process when he inserted small citrus thorns into starfish larvae, then found unusual cells surrounding the thorns.
Feb 8, 2022 · I fetched some rose-thorns and introduced them under the skin of some beautiful starfish larvae ... I was too excited to sleep that night in the expectation of the result of my experiment, and...
Aug 25, 2016 · This year is the centenary of the death of Elie Metchnikoff, the father of innate immunity. His work on phagocytosis has continued to flourish, particularly over the past half century.
- Siamon Gordon
- 2016
Oct 1, 2016 · Metchnikoff discovered that in planarians, hydrozoa, siphonophorae, craspedote medusa, and parenchymula larva, the digestive track is not a cecum but a massive parenchyma. He then realized that the digestion process can be undertaken by specialized cells.
- Jean-Marc Cavaillon, Sandra Legout
- 2016
Jan 1, 2017 · Metchnikoff’s celebrated discovery took place in Messina in 1882: He noticed that certain cells in starfish larvae (Coelenterata) surrounded and engulfed foreign particles during digestion process. He reproduced the same cell behavior by inserting small thorns from garden plants inside the larvae.
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experiment at Messina using starfish larvae, and of leukocyte accumulation by recruitment of amoeboid circulating cells, may be partly myth, but is consistent with his style of research; use of simple, transparent organisms for direct observation and imagina-tive leaps to understand its possible significance for host defence.