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The origin of these viruses appears to be at least 9400 to 14,000 years ago. The Old World and New World dengue strains diverged between 150 and 450 years ago. The European and Far Eastern tick-borne encephalitis strains diverged about 1087 (1610–649) years ago.
Taxonomy. Phylogenetic tree of Flaviviridae using the NS3 protein sequences. The family has four genera: [1] [2] Genus Flavivirus, renamed Orthoflavivirus in 2023, (includes Dengue virus, Japanese encephalitis, Kyasanur Forest disease, Powassan virus, West Nile virus, Yellow fever virus, and Zika virus)
It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, all of which can cause the full spectrum of disease.
Jun 25, 2021 · Aedes aegypti is a native African mosquito and, not coincidently, YF originates in Africa. YFV is transmitted through an urban cycle and wild species cycle.
- Rong Zhao, Meiyue Wang, Jing Cao, Jing Shen, Xin Zhou, Deping Wang, Jimin Cao
- 10.3390/life11070615
- 2021
- Life (Basel). 2021 Jul; 11(7): 615.
Nov 22, 2021 · The Flavivirus genus consists of >70 members including several that are considered significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be roughly categorised into two phenotypes – systemic disease involving haemorrhage exemplified by dengue and yellow Fever virus, and neurological complications associated ...
- Sophie Wilhelmina van Leur, Tiaan Heunis, Deeksha Munnur, Sumana Sanyal
- 10.1080/21505594.2021.1996059
- 2021
- Virulence. 2021; 12(1): 2814-2838.
Apr 30, 2017 · Evaluations of phylogenetic divergence times indicate the origins of the flaviviruses go back around 100,000 years to a common ancestor with the split between mosquito- and tick-borne flaviviruses around 40,000 years ago [ 1 ].
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The flavivirus family derives its name from one of the greatest plagues in history, yellow fever ("flavi"= yellow in Latin). The yellow fever epidemic started hundreds of years ago when the virus and its vector, a mosquito known as Aedes aegypti , were transported to the New World in the water casks of slave ships from West Africa.
