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      • When a mosquito bites a person infected with a dengue virus, the virus enters the mosquito. Then, when the infected mosquito bites another person, the virus enters that person's bloodstream and causes an infection.
      www.mayoclinic.org › diseases-conditions › dengue-fever
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  2. Oct 10, 2018 · The virus binds to host cell receptors (exact receptors are unknown) (1) and enters the host cell (DENV permissive cells include keratinocytes, dendritic cells, endothelial cells, fibroblasts, macrophage, and mast cells), via receptor-mediated endocytosis (2).

  3. Sep 30, 2021 · Structural organization of Dengue virus genome: The viral genome consists of 5′UTR, an ORF, and 3′UTR. The ORF encoding polyprotein serves as a template for the translation of 3 structural proteins (C (Capsid), PrM (Pre-Membrane), and E (Envelope)) and 7 Non-structural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5).

    • Nikita Nanaware, Anwesha Banerjee, Satarupa Mullick Bagchi, Parikshit Bagchi, Anupam Mukherjee
    • 10.3390/v13101967
    • 2021
    • Viruses. 2021 Oct; 13(10): 1967.
  4. As the infected monocytes and macrophages travel through the lymphatic system, the dengue virus spreads throughout the body. During its journey, the dengue virus infects more...

  5. Jun 13, 2019 · In the mosquito vector, DENV enters through viremic blood meal and replicates in the mid-gut. Newly formed virion particles circulate to various mosquito organs and get transmitted to the next host in subsequent bites. Aedes aegypti and Aedes albopictus have intricate immune control to allow DENV production at a sub-pathogenic level.

    • Debica Mukherjee, Sandeepan Das, Feroza Begum, Sweety Mal, Upasana Ray
    • 10.3390/pathogens8020077
    • 2019
    • Pathogens. 2019 Jun; 8(2): 77.
  6. Feb 25, 2015 · DENV infection cycle initiates with the virus attachment to the target cell through the interaction between viral surface proteins and attachment/receptors molecules on the cell surface. This interaction allows the internalization of the virus particle, generally involving receptor-mediated endocytosis.

  7. As the immune response fights the dengue infection, the person’s B cells begin producing IgM and IgG antibodies that are released in the blood and lymph fluid, where they recognize and neutralize...

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