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  1. Aug 2, 2021 · A better understanding of S protein features, structure and mutations facilitate the recognition of the importance of SARS-CoV-2 S protein in viral infection, as well as the development of therapies and vaccines.

    • Ahmed M. Almehdi, Ghalia Khoder, Aminah S. Alchakee, Azizeh T. Alsayyid, Nadin H. Sarg, Sameh S. M. ...
    • 10.1007/s15010-021-01677-8
    • 2021
    • Infection. 2021; 49(5): 855-876.
  2. The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells.

    • T. C. Theoharides, P. Conti
    • 2021
  3. Aug 30, 2021 · By injecting cells with a synthetic mRNA that encodes a viral spike protein, an mRNA vaccine can direct human cells to make a viral spike protein and evoke an immune response without a person ever having been exposed to the viral material.

  4. Aug 16, 2021 · The uniting feature of current genetic COVID-19 vaccines is the provision of mRNAs for the whole, membrane-anchored spike protein (Figs. 1, 2) in tissues after intramuscular application....

    • Franz X. Heinz, Karin Stiasny
    • 2021
  5. Aug 15, 2024 · The viral spike protein is made of two parts: one that binds to the human protein ACE2, which sits on the surface of many kinds of human cells and is the virus’s portal for infection, and another part that changes its shape to move the virus closer to the human cell once it is attached.

  6. Jul 31, 2023 · Scientists explain a key difference between the spike-protein molecules generated by the SARS-CoV-2 mRNA vaccine and those the virus induces.

  7. Feb 10, 2021 · The mRNA vaccines for COVID-19 send those instructions, along with a blueprint of the SARS-CoV-2 spike protein, to the cells, triggering your immune system to generate very protective, high-level neutralizing antibodies. And that’s what gives your body the protection it needs against the virus.