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Cyclohexylamine is produced by two routes, the main one being the complete hydrogenation of aniline using some cobalt- or nickel-based catalysts: [4] C 6 H 5 NH 2 + 3 H 2 → C 6 H 11 NH 2. It is also prepared by alkylation of ammonia using cyclohexanol .
May 16, 2011 · Scientists discovered neurotransmitters are stored in small, bubble-like compartments called vesicles. Each vesicle tends to hold a single kind of neurotransmitter — say, dopamine, which is associated with memory and other cognitive skills, or serotonin, which helps regulate mood.
Studies with rats and dogs have shown that small amounts of cyclamate can be distributed to all tissues (except the brain), although accumulation is negligible. Figure 2 . Schematic of the metabolic routes for cyclamate in several mammalian species.
Jan 13, 2016 · Generally, cyclohexylamine, is readily absorbed & rapidly excreted from the body. After admin to rats, cyclohexylamine appears in body tissues with the highest concn in the lungs, spleen, liver, adrenals, heart, GI tract & kidneys.
Cyclohexylamine is produced from cyclamate by the intestinal flora, for which reason many toxicological studies are available. 1 Toxic Effects and Mode of Action
Dec 8, 2022 · Arylcyclohexylamine (ACH) compounds such as ketamine, phencyclidine and eticyclidine derivatives are of particular concern, given their rapidly increasing use and the absence of detailed toxicity data. First used mainly for their pharmacological properties in anesthesia, their recreational use is increasing.
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Formula: C 6 H 13 N. Molecular weight: 99.1741. IUPAC Standard InChI:InChI=1S/C6H13N/c7-6-4-2-1-3-5-6/h6H,1-5,7H2 Copy. IUPAC Standard InChIKey:PAFZNILMFXTMIY-UHFFFAOYSA-N Copy. CAS Registry Number: 108-91-8.
