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  1. Sep 15, 2015 · Based on my clinical experience and clinical research, I recommend that papaya leave extract to be given from the first day of Dengue fever concurrently with the usual dengue management. This will reduce morbidity and mortality.

  2. Apr 11, 2022 · Other than larvicidal activity, this review also reveals two medicinal potentials of C. papaya leaf juice on dengue infection, namely anti-thrombocytopenic and immunomodulatory effects. C. papaya leaf juice has the potential to be a new drug candidate against dengue disease safely and effectively.

    • 10.3390/nu14081584
    • 2022/04
    • Nutrients. 2022 Apr; 14(8): 1584.
  3. Apr 26, 2021 · This review summarizes all the scientific reports on Carica papaya L. for its ability on three aspects of dengue: antiviral activities, prevention of thrombocytopenia and improvement of immunity during dengue fever. Keywords: Carica papaya, dengue, viral infection, Aedes aegypti virus, thrombocytopenia, immunity, dengue treatment, tropical disease.

    • Md. Moklesur Rahman Sarker, Farzana Khan, Isa Naina Mohamed
    • 10.3389/fphar.2021.610912
    • 2021
    • Front Pharmacol. 2021; 12: 610912.
  4. May 5, 2020 · Carica papaya leaf contains active components such as alkaloids, glycosides, tannins, saponins, and flavonoids, which are responsible for its medicinal activity. Additionally, the leaf juice of papaya increases the platelet counts in people suffering from dengue fever.

    • Surya P Singh, Sanjay Kumar, Sivapar V Mathan, Munendra Singh Tomar, Rishi Kant Singh, Praveen Kumar...
    • 10.1007/s40199-020-00348-7
    • 2020
    • Daru. 2020 Dec; 28(2): 735-744.
  5. Mar 2, 2017 · This systematic review and meta-analysis aims to critically analyze the evidence from controlled clinical trials on the efficacy and safety of CP extract in the treatment of dengue infection.

    • Senaka Rajapakse, Nipun Lakshitha de Silva, Praveen Weeratunga, Chaturaka Rodrigo, Chathurani Sigera...
    • 2019
  6. Jun 16, 2023 · Equally important is the efficiency of the papaya plant against the Aedes mosquito in addition to its action against the virus, so, if demonstrated to be efficient, this plant could reduce dengue load at 2 distinct stages, at the level of transmission as well as the host level 3.

  7. Oct 15, 2015 · This systematic review and meta-analysis was designed to search the available evidence related to the efficacy and safety of C. papaya leaf extract in dengue and to synthesize the evidence in meaningful form through meta-analysis so that inference can be drawn. Materials and Methods: