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  2. Aug 14, 2023 · There are three primary antimicrobials within this class: erythromycin, clarithromycin, and azithromycin. [7] [8] Erythromycin has poor activity against gram-negative and anaerobic organisms.

  3. Erythromycin is a macrolide that acts by inhibiting the translocation reaction during protein synthesis. Erythromycin is inactive against the Enterobacteriaceae and Pseudomonas aeruginosa except under alkaline conditions.

    • John A. Washington, Walter R. Wilson
    • 1985
  4. Aug 14, 2023 · While erythromycin administration is possible via the IV route, the most common formulation of macrolide antimicrobials is in oral dosage forms. This is due to these agents causing significant pain and discomfort around the infusion site parenterally. Additionally, intravenous macrolides have correlations with thrombophlebitis.

  5. Mar 15, 2004 · Bacteriostatic agents (e.g., chloramphenicol, clindamycin, and linezolid) have been effectively used for treatment of endocarditis, meningitis, and osteomyelitis—indications that are often considered to require bactericidal activity.

  6. Oct 6, 2020 · Bacteriostatic antibiotics (left) stop growth and colony-forming units (CFUs) remain stable. By contrast, bactericidal antibiotics (right) kill bacteria and thus the CFUs drop.

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