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  1. Dec 19, 2022 · Research has shown that esketamine can significantly reduce depression symptoms — relief that can last weeks after treatment ends. Though they’re far from perfect treatments, ketamine and esketamine mark a breakthrough, as they’re the only fast-acting antidepressants available.

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  3. Nov 1, 2022 · Ketamine offers a new, fast-acting approach to relieving treatment-resistant depression. Learn the research-backed benefits and how to try it.

    • Rebecca Strong
  4. Dec 29, 2023 · Is ketamine a treatment for depression? What are the risks? Learn about the uses, benefits, and side effects of ketamine.

  5. Feb 15, 2024 · Ketamine is an FDA-approved drug for hard-to-treat depression, but it can cause dissociation and other side effects. Learn about the benefits, risks, and alternatives of ketamine therapy, and how to find a reputable and safe ketamine clinic.

    • Peter Grinspoon, MD
    • (877) 649-9457
    • 4 Blackfan Circle, 4th Floor, Boston, 02115, MA
    • hhp_info@health.harvard.edu
  6. Apr 15, 2024 · In 2019, the Food and Drug Administration (FDA) approved esketamine as a treatment for forms of depression that haven’t improved with standard antidepressants (like citalopram/Celexa or...

  7. Apr 15, 2022 · In 2019, esketamine received FDA approval as an adjunctive treatment for treatment-resistant depression (TRD) in adults. Esketamine was approved under a risk evaluation and mitigation strategy (REMS) that requires administration under medical supervision.

  8. Aug 3, 2023 · This study evaluates the efficacy and acceptability of ketamine for major depression, comparing racemic and esketamine formulations and different dosing approaches. It also examines the time course of antidepressant effects and the risk of dropout.

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