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  1. Sep 29, 2022 · Late-onset sepsis (LOS) usually occurs via the transmission of pathogens from the surrounding environment after delivery, such as contact from healthcare workers or caregivers. A percentage ofLOS may also be caused by a late manifestation of vertically transmitted infection.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  2. Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preterm infants—born at ever-decreasing gestational ages—are at particularly high risk for life ...

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  4. Nov 11, 2022 · Abstract. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality within the neonatal intensive care unit (NICU) and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

    • Sarah A. Coggins, Kirsten Glaser
    • 2022/11/11
    • 10.1542/neo.23-10-e738
  5. May 8, 2021 · Therefore, there is a need for such a review assessing the effects of different antibiotic regimens for lateonset neonatal sepsis. Study characteristics. The evidence is current to March 2021. We included five trials randomising 580 participants. The five trials compared five different antibiotic regimens.

    • Steven Kwasi Korang, Sanam Safi, Chiara Nava, Adrienne Gordon, Munish Gupta, Gorm Greisen, Ulrik Lau...
    • 10.1002/14651858.CD013836.pub2
    • 2021
    • 2021
  6. PowerPoint Presentation. NCCC Guidelines for Management of Late Onset (≥ 7 DOL) Neonatal Sepsis. SUSPECT SEPSIS. OBTAIN TWO BLOOD CULTURES FROM DIFFERENT SITES: One peripheral and one central (if available) or two different peripheral sites Obtain catheterized urine culture & consider lumbar puncture. BEGIN ANTIBIOTICS: Use Oxacillin & Gentamicin.

  7. Jan 6, 2020 · Late onset sepsis (LOS; i.e., sepsis onset >72 h after birth) remains a leading cause of neonatal mortality [].It often presents with nonspecific signs of illness (e.g., temperature instability ...

  8. sepsis in neonates with suspected late-onset sepsis Weak Moderate b. However, in level-2 neonatal units with no facilities for blood culture, the group suggests using serum CRP as a screening tool to rule out sepsis in neonates with a low probability of late-onset sepsis (for example, neonates with apnea, feed intolerance, or fast breathing)