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  1. Sep 29, 2022 · Late-onset sepsis (LOS) usually occurs via the transmission of pathogens from the surrounding environment after delivery, such as contact from healthcare workers or caregivers. A percentage ofLOS may also be caused by a late manifestation of vertically transmitted infection.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  2. Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preterm infants—born at ever-decreasing gestational ages—are at particularly high risk for life ...

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  4. Nov 11, 2022 · Abstract. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality within the neonatal intensive care unit (NICU) and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

    • Sarah A. Coggins, Kirsten Glaser
    • 2022/11/11
    • 10.1542/neo.23-10-e738
  5. Aug 1, 2021 · This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted. After a commissioned evidence-based review by the Agency for Healthcare Research and Quality, an additional extensive and ongoing review of the literature, and supplemental data from published, peer-reviewed studies provided by active ...

  6. Oct 1, 2020 · Neonatal sepsis is divided into early and late onset forms that differ by mode of acquisition and, thus, time of onset. Early onset sepsis (EOS) is the result of vertical bacterial transmission from the mother during the perinatal period.

  7. NCCC Guidelines for Management of Late Onset (≥ 7 DOL) Neonatal Sepsis. SUSPECT SEPSIS. OBTAIN TWO BLOOD CULTURES FROM DIFFERENT SITES: One peripheral and one central (if available) or two different peripheral sites Obtain catheterized urine culture & consider lumbar puncture. BEGIN ANTIBIOTICS: Use Oxacillin & Gentamicin.

  8. Apr 1, 2021 · Neonatal infection is a significant cause of mortality and morbidity in newborn babies. It can lead to life-threatening sepsis, which accounts for 10% of all neonatal deaths. Late-onset neonatal infection (infection that occurs more than 72 hours after birth), is present in 7 of every 1000 newborn babies and is responsible for 61 of every 1000 ...