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  1. Dec 5, 2023 · Late persistent Lyme disease usually occurs in those who did not receive early treatment. It's the most severe stage and can occur months to years following the initial infection. Damage to the joints, nerves, and brain is possible if not treated.

  2. Feb 10, 2023 · In the third stage, you may have symptoms from the earlier stages and other symptoms. This stage is called late disseminated disease. In the United States, the most common condition of this stage is arthritis in large joints, particularly the knees.

  3. There are three stages of Lyme disease. Early localized, or Stage 1, Lyme disease occurs soon after being infected, when the Lyme disease bacteria are still close to the site of the tick bite. Common symptoms of early localized Lyme disease include a rash or mild, flulike symptoms.

  4. Learn the Stages of Lyme Disease. Lyme disease occurs in three stages: early localized, early disseminated, and late disseminated. However, the stages can overlap, and not all patients go through all three.

  5. Prognosis. The prognosis after early treatment of Lyme disease is generally very good. However, the prognosis worsens when diagnosis and treatment are delayed. Most patients with early Lyme disease infection recover with antibiotics and return to their normal state of health.

  6. Jun 16, 2023 · What’s tricky, too, is that the onset of initial symptoms occurs anywhere from three to 30 days after exposure. Clinically, there are three stages of Lyme disease: early localized disease, early disseminated disease, and late disseminated disease.

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  8. Late stage disseminated Lyme disease can result when treatment is unsuccessful or started too late due to unrecognized symptoms or misdiagnosis. The late disseminated stage occurs months or years after initial infection and can have a major impact on a patient’s health and quality of life.

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