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Does MDT increase the frequency and severity of lepra reactions? The evidence available shows that there is a significant reduction in the frequency and severity of ENL (Type II) reactions in MB leprosy patients on MDT. It is possible that this is attributable to the anti-inflammatory effect of clofazimine.
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Dec 1, 2019 · Therefore, in order to make MDT successful, it is a must to promote low-cost high protein balanced diet among leprosy patients receiving MDT, and important to make them understand that MDT along with locally available high protein diet is essential for leprosy cure.
- Ved Prakash Dwivedi, Arindam Banerjee, Indraneel Das, Aparajita Saha, Malabika Dutta, Bhavya Bhardwa...
- 2019
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries.
Jan 2, 2024 · Contrary to popular folklore, leprosy is not highly contagious, and effective treatment is available . Early diagnosis and treatment are necessary to minimize the likelihood of disability involving the eyes, hands, and feet due to neuropathy, as these are often not reversible and may require lifelong care [ 9 ].
Jun 1, 2022 · Up to 70% of individuals with leprosy will experience PNP to some degree following routine MDT. In addition, leprosy patients in reaction requiring corticosteroids are at an increased risk of developing biochemical diabetes, a significant and common comorbidity of leprosy.
- Michael Klowak, Andrea K. Boggild
- Jan-Dec 2022
- 10.1177/20499361221102663
Therefore, in 1981, WHO recommended that all registered patients with leprosy should receive combination therapy with three antibiotics: rifampicin, clofazimine, and dapsone. Global implementation of this highly efective multidrug therapy took about 15 years.
Dec 1, 2019 · The MDT treatment for PB and MB varies from 6 to 12 months respectively, without relapses or recurrences or the development of resistance, with an aim to reduce the grade two physical disabilities [5]. Recent studies by WHO estimated that the global burden of leprosy was dramatically decreased from 5.2 million in 1985 to 176,176 in 2015.
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