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  1. Feb 9, 2023 · Perinatal medicine and neonatology have seen significant advancements in recent decades. Nevertheless, sepsis remains a major medical problem in neonates [].Depending on the time of clinical presentation and the origin of the causative pathogens, it is defined as early-onset sepsis (EOS) when occurring ≤72 h after birth (or by others during the first 7 post-natal days), and as late-onset ...

  2. Nov 2, 2021 · Gandhi and Kondekar propose that I:T ratio >0.27 in term newborns and >0.22 in preterm neonates favor the diagnosis of neonatal sepsis. 60 Murphy and Weiner demonstrated that two normal I:T ratios ...

    • Istemi Han Celik, Morcos Hanna, Fuat Emre Canpolat, Fuat Emre Canpolat, Mohan Pammi
    • 2021
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  4. Feb 24, 2024 · In conclusion, current neonatal sepsis management heavily relies on antimicrobial therapy, emphasizing the need for a judicious and evidence-based approach. Ongoing research and the incorporation of innovative strategies are essential to continually improve outcomes for neonates at risk of or affected by sepsis. 11.2.

  5. Background Neonates are at major risk of sepsis, but data on neonatal sepsis incidence are scarce. We aimed to assess the incidence and mortality of neonatal sepsis worldwide. Methods We performed a systematic review and meta-analysis. 13 databases were searched for the period January 1979–May 2019, updating the search of a previous systematic review and extending it in order to increase ...

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