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  1. Feb 3, 2021 · The most common cause of acute liver failure in the newborn period is the gestational alloimmune liver disease that was previously known as neonatal hemochromatosis. This is followed by viral infections, metabolic diseases, hemophagocytic lymphohistiocytosis, and other rare causes.

  2. Sep 29, 2022 · Describe various clinical and laboratory findings associated with neonatal sepsis. Review the various treatment and management options available for neonatal sepsis. Explain the importance of improving care coordination amongst interprofessional team members to improve outcomes for neonates affected by sepsis.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  3. Feb 1, 2021 · Serum levels of liver enzymes (ALT, AST) increase as a result of hypoxia and damage of liver parenchyma. Increased activities of these liver enzymes are sensitive markers of the impaired liver membrane.

    • Akram Elshafey Elsadek, Naglaa FathyBarseem, Hany Abdelaziz Suliman, Hatem Hamed Elshorbagy, Naglaa ...
    • 2021
  4. May 20, 2024 · To test this hypothesis, we assessed expression changes in the Ang/TIE and arachidonic acid signaling pathways in two human neonatal cohorts most at risk of developing neonatal sepsis:...

  5. Nov 2, 2021 · Neonatal sepsis is a clinical syndrome characterized by nonspecific signs and symptoms caused by invasion by pathogens. 1, 2 Sepsis is deemed culture-proven if confirmed by microbial growth on...

    • Istemi Han Celik, Morcos Hanna, Fuat Emre Canpolat, Fuat Emre Canpolat, Mohan Pammi
    • 2021
  6. Dec 23, 2019 · Key points. Introduction. Neonatal acute liver failure (NALF) is a rare and not well-understood disease. The diagnosis, prognosis, and management have changed over the last 10 to 15 years based on the growing knowledge of the cause and treatment of one of the most common known causes of NALF, gestational alloimmune liver disease (GALD).

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  8. Oct 10, 2023 · Neonatal/early infantile acute liver failure is a devastating condition with rapid progressive hepatocellular injury and poor prognosis compared to older children. Most common etiology includes neonatal hemochromatosis, viral hepatitis, and metabolic/genetic and ischemic causes.

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