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Oct 14, 2021 · 1-Phenylcyclohexylamine | C12H17N | CID 31862 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Jan 1, 2016 · The first arylcyclohexamine to be described was 1-(1-phenylcyclohexyl) amine, in 1907, almost 50 years before the synthesis of PCP . Other analogues reported in the early 1950s included N-ethyl-1-phenylcyclohexylamine (PCE) and 1-(1-phenylcyclohexyl)morpholine (PCMo). While many were not explored further by their initial investigators, chemists ...
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Synthesis and anticonvulsant activity of 1-phenylcyclohexylamine analogs ... Download Free PDF.
Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants and tested for cataleptoid activity and antitonic extensor properties. Various 1-arylcyclohexylamines were synthesized for evaluation as central nervous system depressants. The compounds were prepared by several procedures. 1-(1-Phenylcyclohexyl)piperidine, the first compound of this type ...
Apr 2, 2013 · Solvent (CDCl 3 vs. d 6-DMSO) and protonation effects (free bases vs hydrochloride salts) were studied in order to investigate the impact on shifts and splitting patterns, for example, when attempting to assign separate axial and equatorial proton chemical shifts of NMR spectra. Differentiation between the isomeric 3-MeO-/4-MeO-PCP and PCPy ...
- Jason Wallach, Giorgia De Paoli, Adeboye Adejare, Simon D. Brandt
- 19
- 2014
- 02 April 2013
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide -based reagents used as accelerators for vulcanization. It is a building block for pharmaceuticals (e.g., mucolytics, analgesics, and bronchodilators ). The amine itself is an effective corrosion inhibitor.
Synthesis of deuterium‐labelled drugs of abuse for use as internal standards in quantification by selected ion monitoring. I. Methamphetamine; 2,5‐dimethoxy‐4‐methylamphetamine (DOM); phencyclidine (PCP); and methaqualone. Journal of Labelled Compounds and Radiopharmaceuticals 1976, 12 (1) , 69-78.
