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  2. Aug 11, 2023 · Abstract. Since the emergence of COVID-19, several SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) variants have emerged and spread widely. These variants are produced...

  3. Oct 6, 2020 · Potential antivirals target the different steps of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication, ranging from receptor binding, entry and fusion to...

    • Ben Hu, Hua Guo, Peng Zhou, Zheng Li Shi
    • 2021
  4. Oct 28, 2020 · By contrast, SARS-CoV-2 replicates abundantly in upper respiratory epithelia, where ACE2 is also expressed, and is efficiently transmitted 36 – 38. Different host cell tropism, replication kinetics and transmission of SARS-CoV and SARS-CoV-2 might be determined by S protein–ACE2 binding affinities.

    • Philip V’kovski, Annika Kratzel, Silvio Steiner, Hanspeter Stalder, Volker Thiel
    • 10.1038/s41579-020-00468-6
    • 2021
    • Nat Rev Microbiol. 2021; 19(3): 155-170.
  5. Oct 28, 2020 · Review Article. Published: 28 October 2020. Coronavirus biology and replication: implications for SARS-CoV-2. Philip V’kovski, Annika Kratzel, Silvio Steiner, Hanspeter Stalder & Volker...

  6. Jan 18, 2022 · COVID-19 PCR tests use primers that match a segment of the virus’s genetic material. This allows many copies of that material to be made, which can be used to detect whether or not the virus is present. A positive COVID-19 PCR test means that SARS-CoV-2 is present.

  7. Nov 25, 2021 · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other coronaviruses rely on a cohort of specialized viral proteins to transcribe and replicate their RNA genomes.

    • Brandon Malone, Nadya Urakova, Eric J Snijder, Elizabeth A Campbell
    • 2021
  8. May 12, 2020 · SARS-CoV-2, the causative agent for the pandemic corona virus disease of 2019 (COVID-19) outbreak, was first found in Wuhan, China, and initial analysis of viral RNA obtained from patients hospitalized in late 2019 revealed it was 96% identical at the whole-genome level to a bat SARS-like coronavirus. 7.

    • Cornelia C. Bergmann, Robert H. Silverman
    • 2020
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