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Max Delbrück and Salvador Luria won the 1969 Nobel Prize in Physiology or Medicine in part for this work. History. By the 1940s the ideas of inheritance and mutation were generally accepted, though the role of DNA as the hereditary material had not yet been established.
Feb 5, 2016 · Luria passed his insight to Delbrück, who worked out the expected statistical distribution of the number of mutant cells per culture. Their data decisively rejected the hypothesis that bacteria became resistant only after being exposed to the virus and strongly supported the prediction that the phage-resistant mutations had a constant ...
- Andrew Murray
- 10.1534/genetics.115.186163
- 2016
- Genetics. 2016 Feb; 202(2): 367-368.
Feb 5, 2016 · By addressing these crucial evolutionary questions, Salvador Luria and Max Delbrück won a Nobel Prize and helped to start the field of bacterial genetics. In 1943, it had long been known that bacterial cultures rapidly develop resistance to viral infection.
- Andrew Murray
- 2016
Jun 6, 2017 · In 1943, Salvador Luria along with Delbrück made a spectacular contribution; one often cited as the actual start of microbial genetics (Luria and Delbrück 1943). An E.coli culture incubated with phage was wiped out, except that there were rare cells resistant to infection.
- Bernard S. Strauss
- 10.1534/genetics.117.201517
- 2017
- Genetics. 2017 Jun; 206(2): 641-650.
Feb 5, 2015 · Salvador Luria himself described this experience in an essay in Phage and the Origins of Molecular Biology, a volume of essays dedicated to Luria’s coauthor, Max Delbrück, for Delbrück’s sixtieth birthday , and used the experience for the title of his autobiography as well .
- Philip M. Meneely
- 2016
Mar 7, 2023 · After designing and performing the now-famous “fluctuation test” experiments, Luria enlisted the theoretical expertise of Max Delbrück, which resulted in their seminal paper . Luria and Delbrück made a convincing case in favor of the spontaneous mutation hypothesis by showing that the experimental pattern of variability was inconsistent ...
Nov 25, 2022 · The Nobel didn’t stop them. Luria shared the prize with Max Delbrück and Alfred Hershey for research on bacteriophages, viruses that invade and often kill bacteria. This work tilled the...
