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Scrub typhus or bush typhus is a form of typhus caused by the intracellular parasite Orientia tsutsugamushi, a Gram-negative α-proteobacterium of family Rickettsiaceae first isolated and identified in 1930 in Japan. [2] [3]
Scrub typhus occurs in Southeast Asia and its associated archipelagoes, in northern Australia, and in Japan, where the disease was first described (1899) and systematically investigated (1906–32). During World War II scrub typhus killed or incapacitated thousands of troops who were stationed in rural or jungle areas in the Pacific theatre.
- The Editors of Encyclopaedia Britannica
May 15, 2024 · Overview. Scrub typhus, also known as bush typhus, is a disease caused by bacteria called Orientia tsutsugamushi. Scrub typhus is spread to people through bites of infected chiggers (larval mites). The most common symptoms of scrub typhus include fever, headache, body aches, and rash.
Apr 1, 2020 · Historical reference to the rickettsial disease scrub typhus was first described in China (313 AD) by Hong Ge in a clinical manual (Zhouhofang) and in Japan (1810 AD) when Hakuju Hashimoto described tsutsuga, a noxious harmful disease in the Niigata prefecture.
- Allen L Richards, Ju Jiang
- 10.3390/tropicalmed5020049
- 2020
- Trop Med Infect Dis. 2020 Jun; 5(2): 49.
Mar 17, 2024 · Scrub typhus is one of the most underdiagnosed causes of tropical fevers, often presenting as a fever of unknown origin and causing diagnostic challenges similar to other rickettsioses. When scrub typhus manifests as encephalitis, it can be challenging to differentiate from common viral or bacterial causes of encephalitis.
The disease, scrub typhus, occurs when infected mite larvae accidentally bite humans. This infection can prove fatal if prompt doxycycline therapy is not started. Orientia tsutsugamushi infection was first reported in Japan by Hakuju Hashimoto in 1810, and to the Western world by Theobald Adrian Palm in 1878.
