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Slow intravenous injection of 1% methylene blue
- Treatment includes slow intravenous injection of 1% methylene blue in various fluids. Trace mineral supplements and a balanced diet can help prevent nutritional or metabolic disorders associated with longterm excess dietary nitrate consumption. Feeding grain with high-nitrate forages may reduce nitrite production.
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Treatment of Nitrate and Nitrite Poisoning in Animals Slow IV injection of 1%–2% methylene blue at 4–15 mg/kg; retreatment may be necessary Affected animals should be handled such to minimize stress
- Larry J. Thompson
Treatment includes slow intravenous injection of 1% methylene blue in various fluids. Trace mineral supplements and a balanced diet can help prevent nutritional or metabolic disorders associated with longterm excess dietary nitrate consumption. Feeding grain with high-nitrate forages may reduce nitrite production. For More Information
- Larry J. Thompson
Treatment approach is to evaluate the patient's hydration and electrolyte status and slowly return the animal to normal water and electrolyte balance over several days. Excessive sodium chloride intake can lead to salt toxicosis, also known as hypernatremia or as water deprivation–sodium ion intoxication. Salt toxicosis is unlikely to occur ...
- Larry J. Thompson
- Chemistry of Nitrates and Nitrites
- Where Are Nitrates and Nitrites Found?
- Cancer
- Blue Baby Syndrome
- What else?
- Critics
- What About Animals and Nitrate Poisoning?
- Dogs Specifically
- Thyroid
- Cardiovascular
Nitrates and nitrites are chemical compounds that consist of nitrogen and oxygen. A nitrate is made of a bond between a single nitrogen atom and three oxygen atoms. A nitrite is a bond between a single nitrogen atom and two oxygen atoms. Nitric oxide is a single nitrogen atom bonded to a single oxygen atom.
Nitrates are naturally high in certain vegetables such as leafy vegetables, beetroot juice and celery. Nitrogen is critical in both synthetic fertilizer and organic fertilizer like manure and vegetable compost. Through oxidization – or bonding with air – the nitrogen is transformed into nitrates. Nitrates are also found in fertilizers. When too muc...
The World Health Organization (WHO) and many researchers warn against eating too many processed meats because the nitrites and nitrates may increase one’s chances to develop cancer. When processed meats like bacon and hot dogs are heated, the nitrites interact with the amino acids and cause another chemical to be formed, nitrosamines. Nitrosamines ...
On one side of the argument, we have WHO and major scientists stating that excess intake of well water high in nitrates can lead to “blue baby syndrome” (methemoglobinemia or nitrate/nitrite poisoning). Others contend that methemoglobinemia was not caused by nitrate, but by fecal bacteria that infected the infants and produced nitric oxide in their...
Other adverse medical conditions have been associated with drinking contaminated water such as adverse reproductive outcomes, diabetes and thyroid diseases. Nitrates inhibit iodide uptake by the thyroid, potentially disrupting thyroid function.
Other researchers do not contend with all of that specific evidence However, they say that the human body can tolerate more nitrates and nitrites than the current advisory thresholds. Specifically, they point to natural vegetable sources and the importance of nitrates and nitrites. “Huh?” You ask. Yes. Bacteria in the mouth and gut convert nitrate ...
Keeping with the most widely adopted scientific theory that nitrates cause methemoglobinemia, the disease is caused by an excess intake of nitrates in many other animal species – particularly cows. This is commonly known as nitrate poisoning. Cattle and sheep are ruminant animals – they have a four-chambered stomach. This makes them more susceptibl...
We know that dogs can develop methemoglobinemia, but what about other diseases associated with an overabundance of nitrate intake? Unfortunately, most summaries published by the United States government agencies and WHO reference experiments conducted prior to 1990 that more than likely need to be updated. We attempted to find more recent published...
A research study published in 1973 by Kelley et al. stated that, “Continuous consumption of these sublethal levels of nitrate did notproduce a syndrome of chronic nitrate toxicosis characterized by thyroid dysfunction.” WHO appeared to think otherwise based on studies on Wistar rats. Due to the mounting evidence in human medicine that nitrates and ...
De Laforcade et al. conducted a limited study to find out if nitric oxide concentrations were higher in dogs with either chronic valvular disease (CVD) or dilated cardiomyopathy (DCM) compared to healthy controls, and to determine whether nitric oxide concentrations are correlated with type of cardiac disease, disease severity, medical therapy, or ...
Nitrate poisoning occurs most often in cattle and less often in other ruminants, but it can occur in horses, dogs and cats. It is seldom reported in swine. Clinical diagnosis, treatment, confirmation and prevention of nitrate poisoning is presented with cattle as the principle species; other species will be mentioned where applicable.
Nitrate (NO 3) toxicosis is actually caused by nitrite (NO 2 ). Nitrate itself is not toxic, only when it is converted to nitrite. Many species of animals are susceptible to nitrate poisoning, but ruminants are the most commonly affected.
Dec 14, 2021 · Salt toxicity reflects the ingestion of large amounts of sodium chloride (NaCl); the acute toxic dose in dogs is approximately 4 g/kg.3 This is rare but has been reported in dogs that drink from saltwater pools and oceans or secondary to the administration of saltwater to trigger emesis.4 Ingestion of homemade Play-Doh, which contains high conce...
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