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  1. Jun 15, 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.

  2. Feb 8, 2023 · Systemic sclerosis (SS) is an autoimmune disorder that causes atypical growth of connective tissues. Connective tissue gives your tissues (organs and muscles) strength and...

  3. Sep 29, 2023 · Systemic scleroderma can cause lots of symptoms. It causes thickened skin, usually in larger areas and patches, including on your face and hands. Thick skin usually appears on your fingers or toes and then spreads toward the center of your body.

  4. Jun 15, 2024 · Diagnosis. Because scleroderma can take so many forms and affect so many different areas of the body, it can be difficult to diagnose. After a thorough physical exam, your healthcare professional may suggest blood tests to check for elevated levels of certain antibodies made by the immune system.

  5. Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries.

  6. Scleroderma, or systemic sclerosis, is a chronic connective tissue disease generally classified as an autoimmune disease. The word “scleroderma” comes from the Greek word “sclero”, meaning hard, and the Latin word “derma,” meaning skin.

  7. Overview. Scleroderma is a group of diseases with a common symptom: hardening and tightening of the skin. There are two types of scleroderma: localized and systemic. Localized scleroderma only affects the skin and systemic scleroderma affects the skin, the blood vessels and internal organs.

  8. Systemic scleroderma, also called systemic sclerosis, affects many systems in the body. This is the more serious type of scleroderma and can damage your blood vessels and internal organs, such as the heart, lungs, and kidneys.

  9. Systemic scleroderma, also called systemic sclerosis, affects the skin and internal organs, such as the heart, lungs, gastrointestinal tract, kidneys, and blood vessels. Systemic scleroderma is usually more serious than localized scleroderma and can cause damage to internal organs, which may lead to health complications or even death.

  10. Scleroderma is a rare rheumatic disease that affects connective tissue and the vascular system producing excessive collagen that causes fibrosis in the skin (localized) or in internal organs (systemic sclerosis). The result can be disfigurement and disability, and for some it’s life-threatening. The cause is unknown and there is no cure.

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