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   What is tozinameran?

   • Tozinameran is a single-stranded, 5'-capped messenger RNA (mRNA) produced using a cellfree in vitro transcription from the corresponding DNA templates, encoding the viral spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Dose - 15 µg in 0.15 ml. Liquid for injection. Single dose.

   Evaluation of Full Versus Fractional Dose of COVID-19 Vaccine Given as

   clinicaltrials.gov/ct2/show/NCT05265065

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   Does tozinameran cause internal bleeding?

   • Although no regulatory authority has recognized ICH as an adverse event associated with tozinameran (BNT162b2, Pfizer-BioNTech), fatal and non-fatal cases have been reported [ 4, 5 ]. Autoimmune mechanisms common to Covid genetic vaccines [ 1, 2] are proposed to induce ITP and internal bleeding.

   Potential adverse events in Japanese women who received

   joppp.biomedcentral.com/articles/10.1186/s40545-021-00326-7

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   Does tozinameran cause a high mortality rate?

   • Cumulatively, our analysis reveals a disproportionately high incidence of death by ICH in women who received tozinameran in Japan. The imminent concern would be ITP and CVST, which were observed in 19 patients (8 men and 11 women) who received the Pfizer vaccine in the USA [ 4 ].

   Potential adverse events in Japanese women who received

   joppp.biomedcentral.com/articles/10.1186/s40545-021-00326-7

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   What happened 3 days after taking tozinameran?

   • Three days after the first shot of tozinameran, she developed dysarthria with complaints of headache and nausea. Brain imaging revealed a large hematoma with ventricular rupture. Her platelet count was 216,000/mm 3. She died 5 days after receiving tozinameran. Case 4 was a 69-year-old woman. No underlying condition was specified.

   Potential adverse events in Japanese women who received

   joppp.biomedcentral.com/articles/10.1186/s40545-021-00326-7

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2. www.drugs.com › sfx › sars-cov-2-mrna-tozinameranSars-cov-2 mrna (tozinameran) vaccine Side Effects - Drugs.com

   www.drugs.com › sfx › sars-cov-2-mrna-tozinameran

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   Apr 26, 2023 · Serious side effects. Along with its needed effects, sars-cov-2 mrna (tozinameran) vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor or nurse immediately if any of the following side effects occur while taking sars-cov-2 mrna ...

   • 7.1/10 (17)

3. www.ema.europa.eu › en › medicinesComirnaty | European Medicines Agency

   www.ema.europa.eu › en › medicines

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   Dec 21, 2020 · Overview. Comirnaty is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people from the age of 6 months. The originally authorised Comirnaty contains tozinameran, a messenger RNA (mRNA) molecule with instructions for producing a protein from the original strain of SARS-CoV-2, the virus that causes COVID-19.

4. www.who.int › publications › mPfizer-BioNTech COVID-19 Vaccine, COMIRNATY® (Tozinameran)

   www.who.int › publications › m

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   World Health Organization. Français. This vaccine resource provides key vaccine-specific information for the Pfizer-BioNTech COVID-19 Vaccine Comirnaty®, a messenger RNA (mRNA) based vaccine against coronavirus disease (COVID-19). This document has been updated in English: version 03 June 2022.

5. go.drugbank.com › drugs › DB15696Tozinameran: Uses, Interactions, Mechanism of Action ...

   go.drugbank.com › drugs › DB15696

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   Jul 13, 2020 · Patients experiencing an overdose are at an increased risk of severe adverse effects such as injection site reactions, headache, arthralgia, myalgia, fatigue, chills, and pyrexia. 7,8 Symptomatic and supportive measures are recommended.

6. www.nejm.org › doi › fullSafety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

   www.nejm.org › doi › full

   Dec 10, 2020 · The safety profile of BNT162b2 was characterized by short-term, mild-to-moderate pain at the injection site, fatigue, and headache. The incidence of serious adverse events was low and was similar...

   • Author: Fernando P. Polack, Stephen J. Thomas, Nicholas Kitchin, Judith Absalon, Alejandra Gurtman, Stephen ...

   • Publish Year: 2020

7. labeling.pfizer.com › ShowLabelingPackage leaflet: Information for the user COVID-19 mRNA ...

   labeling.pfizer.com › ShowLabeling

   Dec 22, 2021 · Possible side effects. 5. How to store Pfizer-BioNTech/Comirnaty COVID-19 mRNA Vaccine. 6. Contents of the pack and other information. 1. What Pfizer-BioNTech/Comirnaty COVID-19 mRNA Vaccine is and what it is used for. Pfizer-BioNTech/Comirnaty COVID-19 mRNA Vaccine is a vaccine used for preventing COVID-19 caused by SARS-CoV-2.