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      • Early-onset sepsis (EOS) is defined as the presence of bacteremia or meningitis in the first 72 h of life in neonates admitted to a neonatal intensive care unit (NICU) and in the first 7 days of life in full-term newborns [ 3 ]. Late-onset sepsis (LOS) is defined after 72 h in neonates admitted to NICU and after 7 days in full-term newborns.

      Early and Late Onset Neonatal Sepsis: Epidemiology and ...

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  3. www.ncbi.nlm.nih.gov › pmc › articlesUpdates in Late-Onset Sepsis: Risk Assessment, Therapy and...

    Nov 11, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality within the neonatal intensive care unit (NICU) and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

  4. www.bmj.com › content › 371Neonatal sepsis | The BMJ

    Oct 1, 2020 · Neonatal sepsis is divided into early and late onset forms that differ by mode of acquisition and, thus, time of onset. Early onset sepsis (EOS) is the result of vertical bacterial transmission from the mother during the perinatal period.

  5. www.uptodate.com › contents › clinical-featuresClinical features, evaluation, and diagnosis of sepsis in ...

    Oct 18, 2023 · The epidemiology, clinical features, diagnosis, and evaluation of bacterial sepsis in term and late preterm neonates will be reviewed here. The management and outcome of bacterial sepsis in term and late preterm neonates are discussed separately.

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  7. journals.sagepub.com › doi › fullDifferences in clinical characteristics of early- and late ...

    Aug 20, 2020 · Neonatal sepsis is divided into early-onset (defined as the onset of sepsis in the first three days of life) and late-onset (after day three of life) sepsis. 1 Early-onset sepsis (EOS) is associated with prematurity, a low birth weight, and obstetric complications, such as premature rupture of membranes (PROM), and chorioamnionitis, 7–10 and ...

  8. publications.aap.org › neoreviews › articleLate-onset Sepsis: Epidemiology, Evaluation, and Outcome

    Aug 1, 2010 · Late-onset sepsis significantly increases preterm infant mortality and the risk of cerebral lesions and neurosensory sequelae, including developmental difficulties and cerebral palsy. Early diagnosis of late-onset sepsis contributes to improved neonatal prognosis, but the outcome remains far from satisfactory.