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1. monographs.iarc.who.int › agents-classified-by-theAgents Classified by the IARC Monographs , Volumes 1–135

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   Dec 1, 2023 · Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process. Note: In September 2022, four additional individual Group 1 agents were created by splitting up some existing agent groupings because not all agents in the groups had the same cancer sites with sufficient and limited evidence for cancer in humans.

2. www.ncbi.nlm.nih.gov › pmc › articlesThe IARC Monographs: Updated Procedures for Modern and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Sep 9, 2019 · Advances in the assessment of mechanistic data include the identification of “key characteristics of carcinogens,” which provide a framework for organizing mechanistic data and assessing strengths as well as gaps in evidence ( 7–9 ).

   • Author: Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...

   • Publish Year: 2020

3. People also ask

   What are IARC assessments of carcinogenicity based on?

   • IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review. The evidence comes from epidemiologic studies, animal bioassays, pharmacokinetic/mechanistic experiments, and surveys of human exposure.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   How does the IARC select a carcinogenic agent?

   • The IARC staff makes the final selection of agents for review by taking into account the prevalence and intensity of exposure (of both occupational groups and the general population) and availability of sufficient literature for an evaluation of carcinogenicity, as well as advice from the Advisory Groups.

   IARC Monographs: 40 Years of Evaluating Carcinogenic Hazards to Hum…

   www.ncbi.nlm.nih.gov/pmc/articles/PMC4455595/

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   Do IARC Working Groups review evidence of carcinogenicity?

   • Although IARC working groups have always conducted comprehensive reviews of evidence of carcinogenicity, advances in systematic review methods ( 10–15) provide a basis for more specific guidance to working group members, thereby enhancing consistency and transparency.

   The IARC Monographs: Updated Procedures for Modern and Transparent

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6968684/

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4. www.ncbi.nlm.nih.gov › pmc › articlesIARC Monographs: 40 Years of Evaluating Carcinogenic Hazards ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Feb 24, 2015 · The goal of the Monograph Programme is to assess carcinogenic hazards from occupational, environmental, and lifestyle exposures and agents, thus providing an essential step in the societal decision-making process to identify and then control carcinogenic hazards.

   • Author: Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...

   • Publish Year: 2015

5. www.iarc.who.int › reference › key-characteristicsKey Characteristics of Carcinogens as a Basis for Organizing ...

   www.iarc.who.int › reference › key-characteristics

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   Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis. BACKGROUND: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A-F).

6. www.iarc.who.int › infographics › iarc-monographsIARC Monographs hazard classification – IARC

   www.iarc.who.int › infographics › iarc-monographs

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   Jun 16, 2023 · IARC Monographs hazard classification. This infographic presents the categories used by the IARC Monographs on the Identification of Carcinogenic Hazards to Humans to classify a substance according to the level of certainty that the substance can cause cancer.

7. www.ncbi.nlm.nih.gov › pmc › articlesA new approach to the classification of carcinogenicity - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 15, 2022 · Classification based on the results of the rodent bioassay for cancer and the carcinogenic hazard to humans (United Nations 2019) assumes that carcinogenicity is an intrinsic property of the chemical unrelated to the context of exposure.