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Bonnie Lynn Bassler (born 1962) [2] is an American molecular biologist; the Squibb Professor in Molecular Biology and chair of the Department of Molecular Biology at Princeton University; and a Howard Hughes Medical Institute Investigator.
The research in her laboratory focuses on the molecular mechanisms that bacteria use for intercellular communication. This process is called quorum sensing. Bassler’s research is paving the way to the development of novel therapies for combating bacteria by disrupting quorum-sensing-mediated communication.
Oct 24, 2013 · Bassler: We decided to work on a free-living bacterium, Vibrio harveyi, which clearly would have quorum sensing. Our idea, initially, was that there would be more sensory inputs controlling bioluminescence than Silverman had found controlled bioluminescence in Vibrio fischeri , which lives as a symbiont in a rather controlled environment.
- Ushma S. Neill
- 10.1172/JCI75027
- 2014
- J Clin Invest. 2014 Apr 1; 124(4): 1421-1422.
Sep 28, 2016 · In an era of increasing antibiotic resistance, Dr. Bonnie Bassler’s research could revolutionize medicine by encouraging helpful bacteria and inhibiting the spread of pathogens Live Watch
Jan 1, 2007 · Bonnie Bassler answers questions about bacteria, pursuing a career in biology, and more.
Jun 1, 2006 · As a young scientist-in-the-making, Bonnie Bassler imagined she would grow up to cure cancer. An undergraduate at the University of California, Davis, Bassler joined the lab of Fredrick Troy, who, in the early 1980s, was conducting two major research projects: one on cancer and one on bacterial carbohydrates.
Bassler was born in Chicago, IL, but grew up in Danville, CA, due east of San Francisco. Intellectually curious from a young age, she enjoyed solving logic problems, putting puzzles together, and ‘‘trying to figure out the end of a. www.pnas.org cgi doi 10.1073 pnas.0705870105. Bonnie L. Bassler. book before you got to it,’’ she recalls.
