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Platelet disorders can result from having too few or too many platelets or from impaired platelet function. In general, when platelet counts fall very low there is an increased risk of bleeding. Decreases in platelets may be caused by anti-platelet antibodies, drugs, toxins, or disorders of the bone marrow.
- Anemia in Dogs
Deficiencies in these enzymes lead to shortened red blood...
- Malignant Lymphoma in Dogs
Treatment of high-grade, multicentric canine lymphoma with...
- Blood Parasites of Dogs
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- White Blood Cells of Dogs
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- Bleeding Disorders of Dogs
Affected dogs have prolonged bleeding times and form large...
- Anemia in Dogs
- Fundamental Causes
- Platelet Count
- Potential Problems
The fundamental causes responsible for thrombocytosis in dogs are: 1. It may be a temporary response to epinephrine release. 1. It may be a reaction to a disorder or disease in another part of the body. 1. It may be a sign of an underlying disease in the bone marrow. Temporary thrombocytosis may occur in response to exercise, pregnancy and delivery...
Treatment with some drugs (steroids, vincristine) causes a transient increase in total platelet count. Underactive or absence of spleen is a major site for destroying platelets, and if the spleen is removed, the total platelet count usually increases. The increase may remain for a long time but usually it will settle back into the normal expected r...
The potential problems arising in a reactive thrombocytosis include excessive clot (or thrombus) formation due to the increased number of active platelets and, much less commonly, bleeding as platelet function may also be defective in reactive thrombocytosis. Although both thrombosis and hemorrhage are potential problems, their occurrence in reacti...
Apr 6, 2017 · If your dog is experiencing a type of reactive thrombocytosis, it typically resolves as the infection resolves with time. It is also natural for your dog to experience a high platelet count after surgery or large injury as it is the body’s natural defense mechanism to ensure proper clot formation.
Mar 29, 2022 · Thrombocytosis is indicated by a platelet count that is higher than 1,000,000/µL. Increased blood platelets can lead to abnormal blood circulation and clot formation in the bloodstream. If malformed clots land in your dog’s heart or lungs, it can lead to severe problems and even result in death, as it does in humans.
Jul 3, 2022 · Inflammatory conditions like autoimmune diseases, cancer or trauma, as well as certain infections and iron deficiency, are common causes of a high platelet count. Treatment is directed at the stimulus, and the platelet count returns to normal once resolved.
Affected dogs have prolonged bleeding times and form large bruises easily. A large number of oddly shaped, giant platelets are seen in blood tests. Platelets from dogs with this disorder do not clump together or separate as they normally should. There is no specific treatment.
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Clinical signs include petechiae of the gingivae or skin and ecchymosis, melena, or epistaxis. Platelet counts are usually < 30,000/μL and often < 10,000/μL at the time of diagnosis. If bleeding occurs at a platelet count >30,000, an additional coagulation abnormality may be present.