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What are IARC assessments of carcinogenicity based on?
How does the IARC select a carcinogenic agent?
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How many carcinogenic agents have been evaluated?
Feb 24, 2015 · The terms probably carcinogenic and possibly carcinogenic have no quantitative significance and are used simply as descriptors of different levels of evidence of human carcinogenicity, with probably carcinogenic signifying a higher level of evidence than possibly carcinogenic.
- Neil Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersen, Josep M. Anto, Bruce K. Arms...
- 2015
Dec 1, 2023 · Carcinogenic to humans: 128 agents: Group 2A: Probably carcinogenic to humans 95 agents: Group 2B: Possibly carcinogenic to humans: 323 agents: Group 3: Not classifiable as to its carcinogenicity to humans: 500 agents
Group 1: Carcinogenic to humans; Group 2A: Probably carcinogenic to humans; Group 2B: Possibly carcinogenic to humans; Group 3: Not classifiable as to its carcinogenicity in humans; Perhaps not surprisingly, based on how hard it can be to test possible carcinogens, most are listed as being of probable, possible, or unknown risk.
Sep 9, 2019 · Slightly more than half of all agents evaluated have been classified as possibly carcinogenic, probably carcinogenic, or carcinogenic to humans ( https://Monographs.iarc.fr/agents-classified-by-the-iarc/ ). The IARC Monographs embody principles of scientific rigor, impartial evaluation, transparency, and consistency.
- Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...
- 2020
The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors.
Group 2B: The agent is possibly carcinogenic to humans. This category is used for agents for which there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
In 1991, IARC convened a Working Group on the Use of Data on Mechanisms of Carcinogenesis in Risk Identification, to explore how mechanistic data could be used to identify agents with the potential to cause cancer in humans.