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  1. SUMMARY POINTS. Classic adult pyrexia of unknown origin is fever of 38.3°C or greater for at least 3 weeks with no identified cause after three days of hospital evaluation or three outpatient visits Common causes are infections, neoplasms, and connective tissue disorders.

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  2. Oct 3, 2016 · Pyrexia (also named fever) is the altering upward of the thermoregulatory set point, often secondary to the systemic inflammatory response to a stimulus such as infection. The molecular basis is summarized in Fig. 1 [5, 6].

    • James F. Doyle, Frédérique Schortgen
    • 10.1186/s13054-016-1467-2
    • 2016
    • Crit Care. 2016; 20: 303.
  3. Sep 4, 2023 · Show details. Physiology, Fever. Swetha Balli; Karlie R. Shumway; Shweta Sharan. Author Information and Affiliations. Last Update: September 4, 2023. Go to: Introduction. Fever, or pyrexia, is the elevation of an individual's core body temperature above a 'set-point' regulated by the body's thermoregulatory center in the hypothalamus.

    • 2023/09/04
  4. Sep 25, 2015 · Pyrexia of unknown origin (PUO), also known as fever of unknown origin (FUO), is a grouping of many unre-lated medical conditions that share the feature of persist-ent unexplained fever despite basic investigation. In spite of extensive medical experience and the development of new technologies, this condition remains as dif cult for.

    • Robyn W Beresford, Iain B Gosbell, Iain B Gosbell
    • 2016
  5. The syndrome of pyrexia of unknown origin (PUO) was first defined in 1961 but remains a clinical challenge for many physicians. Different subgroups with PUO have been suggested, each requiring different investigative strategies: classical, nosocomial, neutropenic and HIV-related. This could be expanded to include the elderly as a fifth group.

    • Cristina Fernandez, Nicholas Beeching
    • 10.7861/clinmedicine.18-2-170
    • 2018
    • Clin Med (Lond). 2018 Apr; 18(2): 170-174.
  6. Nov 21, 2023 · Updated: 11/21/2023. Table of Contents. What Is Pyrexia? Hyperthermia and Hyperpyrexia. Lesson Summary. FAQs. Activities. What are the symptoms of pyrexia? Some common symptoms of pyrexia...

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  8. COMMENT. About one week after the first dose of an MMR immunisation it is common to have symptoms of malaise, fever, and a rash, usually lasting 2–3 days. There is also an increased frequency of febrile convulsions at this time. These effects are likely to relate to the measles component and are less common after the second MMR immunisation. 1.

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