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   Should doxycycline be used to treat STIs?

   • In light of increasing prevalence of resistance towards first-line regimens of some STI agents and recently updated recommendations for STI management, doxycycline appears to be an attractive option compared with other available antibiotics for the treatment of some STIs due to its efficacy, good tolerability and oral administration.

   Doxycycline in the management of sexually transmitted infections

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   What is doxycycline used for?

   • Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is an inexpensive broad-spectrum antimicrobial agent largely used in the management of several bacterial infections, particularly involving intracellular pathogens, as well as in the treatment of acne or for the prophylaxis of malaria.

   Doxycycline in the management of sexually transmitted infections

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   Can doxycycline be used to treat chlamydial infections?

   • • Most states permit expedited partner therapy, including provision of packaged medications or prescriptions without evaluation, to limit the spread of STIs. • For chlamydial infections affecting the urethra, rectum, or pharynx, doxycycline, 100 mg orally twice daily for seven days, is most effective.

   Sexually Transmitted Infections: Updated Guideline From the CDC

   www.aafp.org/pubs/afp/issues/2022/0500/p553.html

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2. www.cdc.gov › mmwr › volumesSexually Transmitted Infections Treatment Guidelines, 2021 | MMWR

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   Jul 23, 2021 · Use of acyclovir had no effect on HIV transmission. These findings are consistent with a previous trial that reported no benefit of acyclovir in preventing HIV acquisition among persons seropositive for HSV-2 (89). Doxycycline prophylaxis has been examined for preventing bacterial STIs.

   • Author: Kimberly A Workowski, Laura H Bachmann, Philip A Chan, Christine M Johnston, Christina A Muzny, Ina ...

   • Publish Year: 2021

3. www.cdc.gov › std › treatment-guidelinesSexually Transmitted Infections Summary of CDC Treatment ...

   www.cdc.gov › std › treatment-guidelines

   OR Other parenteral third-generation cephalosporin (e.g., ceftizoxime or cefotaxime) PLUS. doxycycline 100 mg orally 2x/day for 14 days WITH. metronidazole 500 mg orally 2x/day for 14 days. The complete list of recommended regimens can be found in Sexually Transmitted Infections Treatment Guidelines, 2021.

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4. www.verywellhealth.com › std-treatment-4014305Seeking Treatment for Sexually Transmitted Infections

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   Nov 14, 2023 · There are several medications available by prescription for the treatment of viral STIs: Herpes: Acyclovir, famciclovir, valacyclovir. Hepatitis B: Interferon alpha-2b or pegylated interferon , adefovir, entecavir, tenofovir, lamivudine. HIV/AIDS: Antiretroviral medications are used to treat HIV and AIDS.

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6. academic.oup.com › jac › articleDoxycycline in the management of sexually transmitted ...

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   Nov 22, 2017 · According to recently updated recommendations for STI management, doxycycline can be used as the first-line treatment in C. trachomatis infections and as the third-line option in the management of M. genitalium infections whereas it is not recommended any more in N. gonorrhoeae infections because of a high percentage of strains resistant to ...

   • Author: Hélène Peyriere, Alain Makinson, Hélène Marchandin, Jacques Reynes

   • Publish Year: 2017

7. www.aafp.org › pubs › afpChlamydial and Gonococcal Infections: Screening, Diagnosis ...

   www.aafp.org › pubs › afp

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   Preferred chlamydia treatment is a seven-day course of doxycycline, 100 mg taken by mouth twice per day. All nonpregnant people should be tested for reinfection...

8. www.aafp.org › pubs › afpSexually Transmitted Infections: Updated Guideline From the ...

   www.aafp.org › pubs › afp

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   Expedited partner therapy with doxycycline is appropriate for people with chlamydial infection who are uncertain whether sex partners will seek care. Although it is an alternative regimen,...