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  1. Plague of 698–701 (part of first plague pandemic) 698–701 Byzantine Empire, West Asia, Syria, Mesopotamia: Bubonic plague: Unknown 735–737 Japanese smallpox epidemic: 735–737 Japan Smallpox: 2 million (approx. 1 ⁄ 3 of Japanese population) Plague of 746–747 (part of first plague pandemic) 746–747 Byzantine Empire, West Asia, Africa

  2. Plague was present in at least one location in the Islamic world virtually every year between 1500 and 1850. [56] Plague repeatedly struck the cities of North Africa. Algiers lost 30,000–50,000 to it in 1620–1621, and again in 1654–1657, 1665, 1691, and 1740–1742. [57]

  3. Feb 4, 2020 · Cholera, bubonic plague, malaria, leprosy, smallpox, and influenza have been some of the most deadly killers in the world. Here are 10 of the worst pandemics in history. 1. The Plague at Athens (430-427 BC) The earliest recorded pandemic took place in the second year of the Peloponnesian War.

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  5. en.wikipedia.org › wiki › Black_DeathBlack Death - Wikipedia

    Date. 1346–1353. Deaths. 25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. One of the most fatal pandemics in human history, as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3]

    • 75,000,000–200,000,000 (estimated)
  6. Nov 15, 2021 · History’s Seven Deadliest Plagues. SARS-CoV-2 has officially claimed 5 million lives, but credible estimates place the pandemic’s true death toll closer to 17 million. Either count secures COVID-19’s position on our list of history’s deadliest plagues. A masquerade historical scene reconstruction. Plague doctor in medieval old town.

  7. Mar 14, 2020 · Antonine Plague: 165-180: Believed to be either smallpox or measles: 5M: Japanese smallpox epidemic: 735-737: Variola major virus: 1M: Plague of Justinian: 541-542: Yersinia pestis bacteria / Rats, fleas: 30-50M: Black Death: 1347-1351: Yersinia pestis bacteria / Rats, fleas: 200M: New World Smallpox Outbreak: 1520 – onwards: Variola major ...

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    • Prehistoric epidemic: Circa 3000 B.C. About 5,000 years ago, an epidemic wiped out a prehistoric village in China. The bodies of the dead were piled inside a house that was later burned down.
    • Plague of Athens: 430 B.C. Around 430 B.C., not long after a war between Athens and Sparta began, an epidemic ravaged the people of Athens and lasted for five years.
    • Antonine Plague: A.D. 165-180. When soldiers returned to the Roman Empire from campaigning, they brought back more than the spoils of victory. The Antonine Plague, which may have been smallpox, laid waste to the army and may have killed over 5 million people in the Roman empire, wrote April Pudsey, a senior lecturer in Roman History at Manchester Metropolitan University, in a paper published in the book "Disability in Antiquity," Routledge, 2017).
    • Plague of Cyprian: A.D. 250-271. Named after St. Cyprian, a bishop of Carthage (a city in Tunisia) who described the epidemic as signaling the end of the world, the Plague of Cyprian is estimated to have killed 5,000 people a day in Rome alone.
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