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  2. Mar 17, 2020 · Three of the deadliest pandemics in recorded history were caused by a single bacterium, Yersinia pestis, a fatal infection otherwise known as the plague. The Plague of Justinian arrived in...

    • Dave Roos
  3. Nov 15, 2021 · History’s Seven Deadliest Plagues. SARS-CoV-2 has officially claimed 5 million lives, but credible estimates place the pandemic’s true death toll closer to 17 million. Either count secures COVID-19’s position on our list of history’s deadliest plagues. A masquerade historical scene reconstruction. Plague doctor in medieval old town.

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    • Antonine Plague. Deaths: 5 million • Cause: Measles and smallpox. In "The Plague in Rome," painted in 1869, artist Jules Elie Delaunay creates an allegorical representation of the scourge breaking down doors.
    • Plague of Justinian. Deaths: 30-50 million • Source: Rats and fleas. Josse Lieferinxe's "Saint Sebastian Interceding for the Plague Stricken," ca. 1497, depicts Saint Sebastian kneeling to pray before God on behalf of people suffering from or killed by the plague.
    • Black Death. Deaths: 75-200 million • Source: Rats and fleas. The plague in Tournai, then part of France, as depicted in "The Annales of Gilles de Muisit" from the mid-14th century.
    • New World smallpox. Deaths: 25-55 million • Cause: Variola virus. Explorers arrived to the New World bearing more than just turnips and grapes. They also brought smallpox, measles and other viruses for which New World inhabitants had no immunity.
  4. This is a list of the largest known epidemics and pandemics caused by an infectious disease in humans. Widespread non-communicable diseases such as cardiovascular disease and cancer are not included. An epidemic is the rapid spread of disease to a large number of people in a given population within a short period of time; in meningococcal ...

    Event
    Years
    Location
    Disease
    1350 BC plague of Megiddo
    c. 1350 BC
    Megiddo, land of Canaan
    Amarna letters EA 244, Biridiya, mayor of ...
    Hittite Plague /"Hand of Nergal"
    c. 1330 BC
    Near East, Hittite Empire, Alashiya, ...
    Unknown, possibly Tularemia. Mentioned in ...
    430–426 BC
    Greece, Libya, Egypt, Ethiopia
    Unknown, possibly typhus, typhoid fever ...
    412 BC
    Greece ( Northern Greece, Roman Republic ...
    Unknown, possibly influenza
  5. Feb 27, 2019 · The Black Death haunts the world as the worst-case scenario for the speed of disease's spread. It was the second pandemic caused by the bubonic plague, and ravaged Earth’s population. Called the ...

  6. Sep 17, 2010 · The Black Death was a devastating global epidemic of bubonic plague that struck Europe and Asia in the mid-1300s. The plague arrived in Europe in October 1347, when 12 ships from the Black Sea...

  7. Jul 6, 2020 · REFERENCE. Plague was one of history’s deadliest diseases—then we found a cure. Known as the Black Death, the much feared disease spread quickly for centuries, killing millions. The bacterial...

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