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  1. Apr 7, 2020 · Retropolis. History’s deadliest pandemics, from ancient Rome to modern America. Centuries before coronavirus, plague, smallpox, yellow fever and other contagions killed hundreds of millions...

  2. Nov 15, 2021 · It was soon killing 10,000 people a day. Corpses littered public spaces and were stacked like produce indoors. It was perhaps the first major outbreak of bubonic plague the world had seen and the record suggests that it extended across continents, reaching Roman Egypt, the Mediterranean, Northern Europe and the Arabian Peninsula.

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    • The Plague at Athens (430-427 BC) The earliest recorded pandemic took place in the second year of the Peloponnesian War. Originating in sub-Saharan Africa, it erupted in Athens and would persist across Greece and the eastern Mediterranean.
    • Antonine Plague (165-180) The Antonine Plague, sometimes referred to as the Plague of Galen, claimed almost 2,000 deaths per day in Rome. The total death toll was estimated to be around 5 million.
    • Plague of Justinian (541-542) The Plague of Justinian affected the Byzantine Eastern Roman Empire, especially its capital Constantinople as well as the Sasanian Empire and port cities around the Mediterranean Sea.
    • Leprosy (11th century) Although it had existed for centuries, leprosy grew into a pandemic in Europe in the Middle Ages. Also known as Hansen’s disease, leprosy is due to a chronic infection of the bacterium Mycobacterium leprae.
  4. Mar 14, 2020 · Today’s visualization outlines some of history’s most deadly pandemics, from the Antonine Plague to the current COVID-19 event. A Timeline of Historical Pandemics Disease and illnesses have plagued humanity since the earliest days, our mortal flaw.

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  5. Jan 16, 2023 · 1520 | Mexico smallpox epidemic. 1545 | Cocoliztli epidemic. 1576 | Cocoliztli epidemic. 1629 | Italian plague. 1656 | Naples Plague. 1772 | Persian Plague. Modern. 1846 | Cholera pandemic. 1855 | Third plague pandemic. 1889 | Flu pandemic. 1918 | Influenza pandemic.

  6. Mar 17, 2020 · 1. Plague of Justinian—No One Left to Die. BSIP/Universal Images Group/Getty Images. Yersinia pestis, formerly pasteurella pestis, was the bacteria responsible for the plague. Here it's seen...

  7. Dec 7, 2023 · The Black Death. The Black Death (1346–1353 CE) – one of the earliest pandemics with a methodically estimated death toll – killed around 50–60% of Europe’s population, approximately 50 million people, in just 6 years. 3. Researchers have established that many people also died elsewhere – as large outbreaks are also recognizable in ...

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