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  1. Sep 11, 2019 · This Commentary describes the motivation and methodology for the recent update to the Preamble to the IARC Monograph s and highlights the key changes adopted. In addition, the methodology and utility of the hazard identifications provided by the Monographs are communicated more broadly.

  2. Sep 9, 2019 · The IARC Monographs program selects agents for review only if there is evidence of human exposure and some evidence suggesting carcinogenicity. Therefore, the previous group 3 (not classifiable) and group 4 have been combined, and working groups are encouraged to add the statement that an agent is “probably not carcinogenic to humans” when ...

    • Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...
    • 2020
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  4. Jan 1, 2020 · The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert advisory group.

    • Jonathan M Samet, Weihsueh A Chiu, Vincent Cogliano, Jennifer Jinot, David Kriebel, Ruth M Lunn, Fre...
    • 2020
  5. The IARC Monographs programme celebrated its 50th anniversary between December 2021 and December 2022.The first IARC Monographs meeting took place on 13–17 December 1971 in Geneva, Switzerland, and the results were published with the distinctive orange cover as Volume 1 of the IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man in 1972.

  6. BACKGROUND. In 1969, the International Agency for Research on Cancer (IARC) initiated a programme to evaluate the carcinogenic risk of chemicals to humans and to produce monographs on individual chemicals.

    • 1992
  7. The advisory group encouraged the IARC to clarify the purpose and scope of the Monographs evaluations. In this regard, the name of the Monographs series has been changed to the IARC Monographs on the Identification of Carcinogenic Hazards to Humans. This change, although semantic in nature, reflects the impor-

  8. The principles, procedures, and scientific criteria that guide the evaluations are described in the Preamble to the IARC Monographs. Since 1971, more than 1000 agents have been evaluated, of which more than 500 have been identified as carcinogenic, probably carcinogenic, or possibly carcinogenic to humans.

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