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Feb 17, 2022 · Dengue virus (DENV) infection is responsible for the development of dengue illness, which can be either asymptomatic, present mild manifestations or evolve to severe dengue. Thrombocytopenia is an important characteristic during DENV infection, being observed both in mild and severe dengue, although the lowest platelet counts are encountered ...
- Role of Platelet Cytokines in Dengue Virus Infection - PMC
Platelets are the key players involved in immunoregulation...
- Dengue virus binding and replication by platelets - PMC
Thrombin-enhanced Dengue virus binding to platelets....
- Dengue Virus and Platelets: From the Biology to the Clinic
Abstract. Dengue is one of the most important vector-borne...
- Dengue virus binding and replication by platelets - PubMed
Dengue virus (DENV) infection causes ∼200 million cases of...
- Role of Platelet Cytokines in Dengue Virus Infection - PMC
Jan 21, 2024 · One of the hallmarks of dengue is a decrease in platelet count, a condition known as thrombocytopenia. Platelets play a crucial role in blood clotting, and their reduction can lead to bleeding complications. The dengue virus affects bone marrow, where platelets are produced, leading to their decreased production and an increased rate of ...
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How do platelets replicate and produce infectious dengue virus (DENV)?
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How is dengue virus protein translated by platelets?
A common symptom in more severe cases is thrombocytopenia or loss of platelets. Platelets are small blood cells that lack a nucleus and are important for blood clotting and immunity. Platelets from patients with dengue have been shown to contain virus-like particles; however the involvement of platelets in dengue virus infections is unclear.