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  1. Mar 25, 2020 · In this review, we aim to highlight the research on B420 related to obesity, metabolic health, and the microbiota. Current research supports the hypothesis that gut dysbiosis leads to an imbalance in the inflammatory processes and loss of epithelial integrity.

    • Henna-Maria Uusitupa, Pia Rasinkangas, Markus J. Lehtinen, Sanna M. Mäkelä, Kaisa Airaksinen, Heli A...
    • 2020
  2. hcp.howaru.com › strains › b420B420™ - HCP

    B lactis B420™ has been documented in more than 60 scientific studies, including 16 clinical trials. It has been demonstrated in clinical trials to survive intestinal passage, and in vitro studies have shown excellent adhesion to human colonic mucus. 1-3 The primary health attributes of B420™ are weight management and metabolic health ...

  3. Bifidobacterium lactis 420 is one such probiotic that has been studied in preclinical and clinical studies to have an impact on overall GI health, improved glucose intolerance, and body weight regulation. B420 and Adiposity in Human Clinical Trial.

  4. Jun 11, 2021 · A study published earlier this year showed that supplementation with B. lactis 6 420 (B420) reduced the impact of a heart attack 6. We know that gut health and heart health are closely connected to each other, and this is supportive of that concept.

  5. May 31, 2019 · Fast forward to 2017, when DuPont launched HOWARU® Shape, a probiotic formulation that reduces weight gain in obese and overweight people and contains, yes, the now heroic B420™. It’s a much-needed breakthrough considering that the obesity rate worldwide has nearly tripled since the mid-1970s.

  6. Bifidobacterium animalis ssp lactis 420 has three key potential mechanisms of action that may explain its effects of reducing energy intake in the clinical study. Animal studies demonstrate that B420 may increase levels of the anorectic (appetite-reducing) gut peptide GLP-11.

  7. Oct 30, 2023 · Danilo et al. 151 found that administration of B. lactis B420 for 4 weeks or 7 days significantly mitigated myocardial infarct sizes in mice following I/R. The epigenetic mechanisms of B....

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