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Why is the bursa of Fabricius important?
How important is the bursa of Fabricius for the pathogenesis of MD?
Is the bursa of Fabricius important for the pathogenesis of Marek's disease?
Nov 27, 2015 · Different structures have been identified as bursa equivalents in mammals, including gut-associated lympho-epithelial tissue s (GALT) tissues (Cooper et al. 1966b) and the bone marrow in primates, including humans. The lymphoid tissues in the walls of the alimentary, respiratory, reproductive and urinary tracts are collectively termed mucosa ...
- Domenico Ribatti
- 2015
Sep 12, 2022 · The importance of the bursa of Fabricius (BF) for the pathogenesis of Marek’s disease (MD) has been studied since the late 1960’s. In this review, the results of these studies are analyzed in the context of the developing knowledge of the immune system of chickens and the pathogenesis of MD from 1968 to 2022.
May 1, 1970 · 01 May 1970. Article history. PDF. Split View. Cite. Permissions. Share. Abstract. The normal ontogeny of the bursa of Fabricius is necessary for the successful genesis of antibody-mediated immunity, while the avian thymus appears to control cell-mediated immunity.
- Bruce Glick
- 1970
Jan 1, 2022 · The bursa of Fabricius is critical to the normal development of B lymphocytes and the antibodies they go on to produce. While antibody production and B cells are common to all vertebrates, the bursa as an organ of primary B-cell lymphopoiesis is unique to birds and was first implicated in the development or generation of antibody responses ...
Humans. Hieronymus Fabricius ab Aquapendente (1533-1619) described the homonymous bursa in the "De Formatione Ovi et Pulli", published posthumously in 1621. He also included a figure in which the bursa was depicted. We here present the figure of the bursa of Fabricius, along with corrections of some mislabe …
Dec 16, 2021 · Via the blood circulation, IBDV infected peripheral blood mononuclear cells (PBMCs) and was transferred to the bursa of Fabricius to damage the IgM + B lymphocyte population. Subsequently, the single-cell RNA sequencing (scRNA-seq) results suggested the more detailed response of different bursal cell populations (B cells, epithelial cells ...
Nov 15, 2018 · The bursa of Fabricius, the primary lymphoid organ for B cell development found only in birds, offers novel approaches to study B cell differentiation at various developmental stages. Here,...
