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  1. A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port.

  2. Nov 16, 2023 · 2024 dates: In 2024, there are two available itineraries in September and November. Grand Heartland Cruise: St. Paul to New Orleans. Length: 15 days. Price: Starts at $9,455 per person. This...

  3. Get the latest deals for Mississippi River cruises on Cruise Critic. Find and plan your next cruise to Mississippi River with cabin price comparison, variety of departure ports and...

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  5. Our 12 unique itineraries provide guests more ways to explore the Mississippi than any other cruise line, while the sophisticated comfort of our modern riverboats offers the largest staterooms, private balconies, and complimentary excursions at every port. Receive Free Airfare & Savings up to $1,000* on select Lower Mississippi River Cruises.

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    • Best Cruise For Civil War History: Lower Mississippi
    • Best Cruise For Music: Lower Mississippi
    • Best Cruise For Art and Architecture: Upper Mississippi
    • Best Extended Cruise: Complete Mississippi
    • Bottom Line

    The Deep South attracts history buffs with its Civil War battlefields and cemeteries and 18th- and 19th-century mansions guarded by regiments of live oaks. Both cruise lines offer a Lower Mississippi river cruise, sailing round-trip from New Orleans, but only one features multiple excursions geared to those with a keen interest in the 19th-century ...

    If you love the musical genres of the South, a Mississippi River cruise from New Orleans to Memphis (or vice versa) should be your choice. From Crescent City, the birthplace of American jazz, to Memphis, known as the Home of the Blues and the Birthplace of Rock 'n Roll, this itinerary celebrates the region's homegrown rhythms. Both cruise lines off...

    An Upper Mississippi cruise between St. Louis, Missouri, and St. Paul, Minnesota, provides access to some of the top architectural landmarks and artistic treasures of the American Heartland — from Eero Saarinen's soaring Gateway Arch to Frank Lloyd Wright's inimitable Taliesin. Both cruise lines offer Upper Mississippi sailings from July through Se...

    Want it all? You can visit up to 20 ports in as many as nine states on a 22-day Mississippi River journey from New Orleans to St. Paul. These itineraries are offered by both American Cruise Lines and Viking, and are perfect for seniors with plenty of time to explore. American Cruise Lines offers the 22-day Complete Mississippi Cruiseaboard three 18...

    History buffs and Americana lovers will find plenty to enjoy on a Mississippi River cruise. Your ship will stop in major cities and lesser-known towns, offering excursions to historic sites and evenings spent enjoying locally inspired cuisine and regional music. The two cruise lines sailing America's most legendary river offer itineraries for every...

    • Donna Heiderstadt
  6. What cruise lines travel the Mississippi River? Planning a Mississippi River cruise? Check out Cruise Critic's expert Mississippi River planning tips, itineraries, photos, FAQs and...

  7. May 31, 2024 · From $15,999. |. 22 Days. |. 16 Guided Tours. |. 1 Country. Itinerary. Dates & Pricing. Resources. Americana sights, sounds & flavors. PRICE & BUILD. REQUEST A QUOTE. Revel in the charm of “America’s Great River” as you set sail along the Mississippi.

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