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What is a positive HIV Western Blot (WB) test?
When does a HIV western blot become positive?
Is a WB band a sign of HIV infection?
ASTPHLD has proposed that a positive test result be defined by the presence of any two of the following bands: p24, gp41, and gp120/160 (13). The Consortium for Retrovirus Serology Standardization (CRSS) has defined a positive test result as the presence of either p24 or p31, plus a diffuse envelope band (i.e., gp41 or gp120/160) (14).
Oct 7, 2023 · The HIV Western blot typically becomes positive after about 5 to 6 weeks following initial HIV infection; as more protein bands become detectable, the Western blot typically evolves from a pattern of negative, then indeterminate, then positive.
Generally, a specimen must show a positive reaction with a minimum of one core band and one envelope band to be judged positive by Western blot. Specimens that have bands present but do not fulfill the criteria for positivity are called Western blot indeterminate, and a follow-up specimen should be requested, usually collected three to four ...
- Margaret Fearon
- 10.1155/2005/515063
- 2005
- Jan-Feb 2005
Confirmatory Western blot testing identifies antibodies with affinity for specific HIV antigens. Indeterminate Western blot antibody patterns necessitate subsequent testing or alternative methods for interpretation. A “window” period of up to 3 or more months follows acute HIV infection before seropositivity occurs.
- James M. Steckelberg, Franklin R. Cockerill
- 1988
The CDC defines a positive HIV Western Blot (WB) test as having at least 2 of the following bands: p24, gp41, gp120/160. • Indeterminate results occur when there are 1 or more positive bands that do not
- 111KB
- 4
Jun 12, 2019 · The most common WB band patterns were p24, gp160 and p24, and gp160. The follow-up study revealed that the highest negative and positive conversion rates of HIV antibodies were in samples with a single p24 band (80.28%), and with gp160 and p24 bands (86.21%), respectively.
May 3, 2021 · Procedure. Cost. Accuracy. Takeaway. Yoshiyoshi Hirokawa / Getty Images. The Western blot test is an antibody test that’s done on a blood sample. It’s used to confirm or disprove the results of...
