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  1. Feb 10, 2023 · Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock. This is a dramatic drop in blood pressure that can damage the lungs, kidneys, liver and other organs.

  2. May 3, 2024 · Sepsis is a life-threatening condition that happens when the bodys immune system has an extreme response to an infection, causing organ dysfunction (4). The body’s reaction causes damage to its own tissues and organs and it can lead to shock, multiple organ failure and sometimes death, especially if not recognized early and treated promptly.

  3. Mar 21, 2019 · Sepsis is a medical emergency that describes the body’s systemic immunological response to an infectious process that can lead to end-stage organ dysfunction and death.

  4. Aug 29, 2013 · In 1992, an international consensus panel defined sepsis as a systemic inflammatory response to infection, noting that sepsis could arise in response to multiple infectious...

  5. Sepsis is defined as the systemic immune response syndrome (SIRS). In addition to sepsis, the term severe sepsis is defined as sepsis associated with organic dysfunction, hypoperfusion and hypotension, and the term septic shock as a condition of sepsis with arterial hypotension insensitive to fluid replacement.

  6. Feb 1, 2017 · Sepsis is now defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. The consensus document describes organ dysfunction as an acute increase in total Sequential Organ Failure Assessment (SOFA) score two points consequently to the infection.

  7. Nov 1, 2014 · Severe sepsis has been defined as sepsis plus evidence of organ dysfunction (eg, hypotension, oliguria, and metabolic acidosis), and septic shock has been defined as sepsis with persistent signs of hypotension despite fluid resuscitation. 1. , 2.

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