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  1. Oct 12, 2023 · But it often takes about 2 to 4 days for symptoms to fully resolve. Recent studies show that Paxlovid is about 37% effective in preventing hospitalization and death. But when looking only at death prevention, it’s about 84% effective. Most people will take Paxlovid for 5 days.

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    • How does Paxlovid work? Paxlovid is an antiviral therapy that consists of two separate medications packaged together. When you take your three-pill dose, two of those pills will be nirmatrelvir, which inhibits a key enzyme that the COVID virus requires in order to make functional virus particles.
    • When should I take Paxlovid? You have to take Paxlovid within five days of developing symptoms. Like all antivirals, Paxlovid works best early in the course of an illness—in this case, within the first five days of symptom onset, says Jeffrey Topal, MD, a Yale Medicine infectious diseases specialist who is involved in determining COVID-19 treatment protocols for Yale New Haven Hospital patients.
    • How often do I take Paxlovid? The standard dose is three Paxlovid pills twice daily for five days for a full course that adds up to 30 pills. It helps that the pills are packaged in a “dose card,” basically a medication blister pack that allows you to punch out the pills as needed.
    • Is Paxlovid similar to Tamiflu? “I think it's a good comparison,” says Dr. Roberts. Tamiflu is an antiviral drug that reduces flu symptoms. Both are prescription-only oral antiviral pills given early in illness.
  2. May 9, 2024 · Paxlovid rebound typically happens within a week after you've taken Paxlovid to treat COVID-19. With Paxlovid rebound, either your COVID-19 symptoms return or you test positive after testing negative.

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  3. How long does it take to work? Paxlovid starts to work soon after you take it. It works best when taken as soon as possible after getting a positive COVID-19 test and within 5 days of your symptoms starting.

  4. To be effective, Paxlovid must be started within five days of symptoms appearing. Treatment involves taking three pills, twice a day for five days. However, Paxlovid is not for everyone, including people with severe kidney disease.

  5. Feb 4, 2023 · How long does it take for Paxlovid to kick in? Paxlovid is given in a five-day course with three pills taken twice a day. Most people report feeling better by the second or third day on the...

  6. Jan 11, 2024 · As hospitalizations and deaths from Covid-19 rise, fueled by a fast-moving new variant that now accounts for a majority of U.S. cases, Paxlovid can help protect patients from some of the worst...

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