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What is methyldopa used for in pregnancy?
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What is methyldopa used for?
Methyldopa, sold under the brand name Aldomet among others, is a medication used for high blood pressure. [1] It is one of the preferred treatments for high blood pressure in pregnancy. [1] For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred. [1]
- Alpha-2 Adrenergic Receptor Agonist
Antihypertensives are a class of drugs that are used to...
- 3-O-Methyldopa
Infobox references. 3-O-Methyldopa ( 3-OMD) is one of the...
- Methyl group
Methyl group. In organic chemistry, a methyl group is an...
- Alpha-2 Adrenergic Receptor Agonist
Jul 10, 2023 · Methyldopa is a medication used in the management and treatment of hypertension. It is in the centrally acting anti-hypertensive class of drugs. This activity reviews the indications, actions, and contraindications for methyldopa as a valuable agent in the management of hypertension. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off ...
- Mohit Gupta, Yasir Al Khalili
- 2023/07/10
ChEBI. Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha (α)-2 adrenergic receptors ...
Methyldopa works by binding to alpha (α)-2 adrenergic receptors as an agonist, leading to the inhibition of adrenergic neuronal outflow and reduction of vasoconstrictor adrenergic signals. 1 Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. 7.
DrugInteractionMethyldopa may decrease the excretion ...The risk or severity of adverse effects ...The therapeutic efficacy of Methyldopa ...The therapeutic efficacy of Methyldopa ...Jan 10, 2020 · Methyldopa (meth" il doe' pa) is a centrally active sympatholytic agent that reduces sympathic drive to the heart and peripheral circulation, leading to decreased cardiac output and lowered peripheral arterial resistance. Introduced in 1960, methyldopa rapidly became a leading antihypertensive agent, but in the last two decades its use has ...
