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Overview. Volume 100 of the IARC Monographs, A Review of Human Carcinogens, covers all agents previously classified by IARC as "carcinogenic to humans (Group 1)" and was developed by six separate Working Groups: Pharmaceuticals; Biological agents; Arsenic, Metals, Fibres, and Dusts; Radiation; Personal Habits and Indoor Combustions; Chemical ...
- Overview
- The Problem
- Causes
- Risk Factors
- Reducing The Burden
- Prevention
- Early Detection
- Treatment
- Palliative Care
- Who Response
Cancer is a generic term for a large group of diseases that can affect any part of the body. Other terms used are malignant tumours and neoplasms. One defining feature of cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs; the latte...
Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020 (1). The most common in 2020 (in terms of new cases of cancer) were: 1. breast (2.26 million cases); 2. lung (2.21 million cases); 3. colon and rectum (1.93 million cases); 4. prostate (1.41 million cases); 5. skin (non-melanoma) (1.20 million cases); and ...
Cancer arises from the transformation of normal cells into tumour cells in a multi-stage process that generally progresses from a pre-cancerous lesion to a malignant tumour. These changes are the result of the interaction between a person's genetic factors and three categories of external agents, including: 1. physical carcinogens, such as ultravio...
Tobacco use, alcohol consumption, unhealthy diet, physical inactivity and air pollution are risk factors for cancer and other noncommunicable diseases. Some chronic infections are risk factors for cancer; this is a particular issue in low- and middle-income countries. Approximately 13% of cancers diagnosed in 2018 globally were attributed to carcin...
Between 30 and 50% of cancers can currently be prevented by avoiding risk factors and implementing existing evidence-based prevention strategies. The cancer burden can also be reduced through early detection of cancer and appropriate treatment and care of patients who develop cancer. Many cancers have a high chance of cure if diagnosed early and tr...
Cancer risk can be reduced by: 1. not using tobacco; 2. maintaining a healthy body weight; 3. eating a healthy diet, including fruit and vegetables; 4. doing physical activity on a regular basis; 5. avoiding or reducing consumption of alcohol; 6. getting vaccinated against HPV and hepatitis B if you belong to a group for which vaccination is recomm...
Cancer mortality is reduced when cases are detected and treated early. There are two components of early detection: early diagnosis and screening.
A correct cancer diagnosis is essential for appropriate and effective treatment because every cancer type requires a specific treatment regimen. Treatment usually includes surgery, radiotherapy, and/or systemic therapy (chemotherapy, hormonal treatments, targeted biological therapies). Proper selection of a treatment regimen takes into consideratio...
Palliative care is treatment to relieve, rather than cure, symptoms and suffering caused by cancer and to improve the quality of life of patients and their families. Palliative care can help people live more comfortably. It is particularly needed in places with a high proportion of patients in advanced stages of cancer where there is little chance ...
In 2017, the World Health Assembly passed the Resolution Cancer prevention and control in the context of an integrated approach (WHA70.12) that urges governments and WHO to accelerate action to achieve the targets specified in the Global Action Plan for the prevention and control of NCDs 2013-2020and the 2030 UN Agenda for Sustainable Development t...
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Feb 4, 2020 · The global cancer burden is expected to reach 29 million new cancer cases per year by 2040, a 62% increase on the estimated 18.1 million cancers in 2018.
Epidemiology of HPV-associated cancers past, present and future: towards prevention and elimination. In a new review article, researchers from the International Agency for Research on Cancer (IARC) ... IARC hosts second annual meeting of DISCERN project. Researchers from the International Agency for Research on Cancer (IARC) are hosting the ...
National and international health agencies use the Monographs as a source of scientific information on known or suspected carcinogens and as scientific support for their actions to prevent exposure to these agents. Individuals, too, use the information and conclusions from the Monographs to
Mar 30, 2012 · List of Classifications by Cancer Site. We are pleased to announce the publication of a list of carcinogenic agents - by cancer site - with sufficient or limited evidence in humans. The list will be updated regularly as new classifications are announced. See List of Classifications by Cancer Site IARC Monographs website.
D. McGregor, Unit of Carcinogen Identification and Evaluation (Responsible Officer)1 C. Partensky, Unit of Carcinogen Identification and Evaluation J. Rice, Unit of Carcinogen Identification and Evaluation (Head of Programme) J. Wilbourn, Unit of Carcinogen Identification and Evaluation Technical assistance S. Egraz M. Lézère A. Meneghel D ...
