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Dutch physician Pieter Pel first proposed a tissue stage of the malaria parasite in 1886, presaging its discovery by over 50 years. This suggestion was reiterated in 1893 when Golgi suggested that the parasites might have an undiscovered tissue phase (this time in endothelial cells). [75]
Jul 17, 2000 · Alphonse Laveran, a French army doctor, described the malarial parasite--and proposed that it caused malaria--in 1880.
Feb 1, 2010 · The discovery that malaria parasites developed in the liver before entering the blood stream was made by Henry Shortt and Cyril Garnham in 1948 and the final stage in the life cycle, the presence of dormant stages in the liver, was conclusively demonstrated in 1982 by Wojciech Krotoski.
The research occupied a century, beginning in 1880 when Laveran found the first malaria parasite in the blood, and continued with the work of Golgi (periodicity in blood 1885), Danilewsky (avian parasites 1889), MacCallum (exflagellation of microgametocyte, origin of relapses 1980).
Apr 10, 2024 · Our understanding of human malaria parasites began officially in 1880 with their discovery in the blood of malaria patients by Charles Louis Alphonse Lavéran (1845–1922), a French army officer working in Algeria.
Sep 1, 2017 · Laveran’s illustration of the various stages of in the life cycle of malaria parasites and their telltale pigment (black dots), published in the bulletin of the Société Médicale des Hôpitaux de Paris in 1881.
Liver Phase. The liver phase of malaria begins when the female anopheline mosquito injects the sporozoite stage of the parasite into the human host during a blood meal (see Chapter 2, Figure 2-3 ). After just a few minutes, the sporozoites arrive at the liver and invade the liver cells (hepatocytes).
