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  2. Nov 11, 2014 · The general structure of B. burgdorferis cell envelope is exceptional and differs significantly from the typical Gram-negative bacteria. LPSs are usually outer membrane components of Gram-negative bacteria; however, B. burgdorferi lacks LPS (Takayama et al., 1987), and has immunoreactive glycolipids instead (Ben-Menachem et al., 2003).

    • Fig. 1

      The spirochaete bacterium Borrelia burgdorferi sensu lato is...

    • ​ And7) 7

      Composition analysis of B. burgdorferi indicates the...

  3. Borrelia burgdorferi is named after the researcher Willy Burgdorfer, who first isolated the bacterium in 1982. [6] Borrelia burgdorferi is a microaerophile, requiring small amounts of oxygen in order to undergo glycolysis and survive. Like all other Borrelia sps., this bacterium is also gram-negative and a spirochete.

  4. Feb 21, 2017 · B. burgdorferi is often referred to as a gram-negative “like” bacterium because it is void of lipopolysaccharide (LPS) in its OM, but has a similar membrane organization. The unique helical shape of spirochetes is due to its composition of the lipid bilayer OM, a periplasmic space containing peptidoglycan and endoflagella, and a second ...

    • Jenny A. Hyde
    • 10.3389/fimmu.2017.00114
    • 2017
    • Front Immunol. 2017; 8: 114.
  5. May 31, 2019 · B. burgdorferi is a motile, Gram-negative, pathogenic spirochete with a highly segmented genome composed of a linear chromosome and about 20 linear and circular genomic plasmids 1, 8. It exists in an enzootic life cycle alternating between specific Ixodes ticks and vertebrates 9 .

    • Christa Winslow, Jenifer Coburn
    • 2019
  6. Feb 28, 2024 · Borrelia burgdorferi is a helical-shaped spirochete that is poorly gram-stained (other spirochetes do not take up Gram stain). The cells stain a weak Gram-negative as safranin is the last dye used, but Borrelia burgdorferi is not classified as either Gram-positive or Gram-negative.

  7. Jun 27, 2022 · The causative agent, B. burgdorferi is a Gram-negative pathogenic spirochete with a segmented genome composed of a linear chromosome and numerous linear and circular genomic plasmids. Over the years, new pathogenic species of Borrelia have been discovered commonly named B. burgdorferi sensu lato, including species like B. afzelii and B. garinii.

  8. Borrelia burgdorferi one of the causative species of Lyme disease (borreliosis). Magnified 400 times. Lyme disease, or borreliosis, is caused by spirochetal bacteria from the genus Borrelia, [1] which has 52 known species.

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