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  1. May 27, 2023 · Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause extreme muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low.

  2. Mar 31, 2022 · Simvastatin is the most likely to cause muscle pain, and fluvastatin is the least likely. Of course, this isn’t written in stone, since it’s possible for any statin to have this effect. Figuring out which statin doesn’t cause muscle pain for you may require some trial and error. Can muscle pain from statins be dangerous or life-threatening?

  3. Mar 5, 2021 · One group took 20 milligrams of atorvastatin per day for 2 months, while another took a placebo. The researchers found little difference between rates of muscle pain in either group. They...

  4. Mar 19, 2024 · Research has shown that the gene atrogin-1 may be the source of muscle pain in those taking statins. This gene turns on at the beginning stages of the breakdown of muscle, which is associated with illnesses such as cancer, sepsis, and AIDS.

  5. Jul 18, 2023 · Statin-related muscle pain, if it happens at all, usually happens within the first few months after you start the drug or raise the dose. You may feel a constant soreness or weakness in your...

  6. dark-colored urine. diarrhea. joint pain. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs. red skin lesions, often with a purple center sore. red, irritated eyes. sore throat. sores, ulcers, or white spots in the mouth or on the lips.

  7. Nov 17, 2022 · Although mild muscle pain is a relatively common side effect of statins, some people who take statin medications to lower their cholesterol may have severe muscle pain. This intense pain may be a symptom of rhabdomyolysis (rab-doe-my-OL-ih-sis), a rare condition that causes muscle cells to break down.

  8. Feb 15, 2017 · atorvastatin (Lipitor) pitavastatin (Livalo) lovastatin (Mevacor) pravastatin (Pravachol) simvastatin (Zocor) Rhabdomyolysis sounds scary, but the average statin user does not have to worry about...

  9. Aug 9, 2019 · Exercise. There is some evidence that people who have exercised regularly before taking statins are less likely to experience muscle pain and cramping. Although gentle stretching may relieve muscle cramps, beginning a new vigorous exercise regimen while taking a statin may increase the risk of muscle pain. Ramp up your lifestyle changes.

  10. May 16, 2022 · A 2019 study also suggests that statins may cause the release of calcium from your muscles, causing a number of symptoms, including muscle pain and weakness. What are the risk factors for statin ...

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