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- A substantial proportion of very preterm infants continue to suffer late-onset sepsis, particularly those born at the lowest GAs. Infected infants had higher mortality, and survivors had increased risks of technology-dependent chronic morbidities.
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Nov 11, 2022 · Gestational age (GA)-specific patterns of immune function place preterm infants at increased risk of infection, adverse or sustained inflammation, and organ dysfunction. 17–19 Moreover, microbial colonization and aberrations in microbiome development are implicated in increased susceptibility to LOS. 3 20 Specifically, prolonged empiric ...
- Neonatal Sepsis - StatPearls - NCBI Bookshelf
Preterm neonates are at higher risk for sepsis/infection...
- Risk Factors and Prevention of Late Onset Sepsis in Premature ...
Late-onset sepsis in premature infants is a major cause of...
- Cause of preterm birth and late-onset sepsis in very preterm ...
Late-onset sepsis risk differs according to the cause of...
- Neonatal Sepsis - StatPearls - NCBI Bookshelf
Nov 11, 2022 · Late-onset sepsis incidence rates in 2018 to 2020 have plateaued, and remained alarmingly high among infants born at the lowest gestational ages. Infected very preterm infants had lower survival, and survivors had increased adjusted risks of technology-dependent chronic morbidities.
Feb 24, 2021 · Late-onset sepsis risk differs according to the cause of preterm birth. Compared with those born after preterm labor, infants born very preterm because of hypertensive disorders of...
- Mathilde Letouzey, Laurence Foix-L'Hélias, Héloïse Torchin, Ayoub Mitha, Andrei S Morgan, Andrei S M...
- 2021
Nov 1, 2022 · Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.