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  1. Oct 27, 2022 · Sodium nitrite causes increased methemoglobin, resulting in systemic hypoxia, metabolic acidosis, and cyanosis. Since sodium nitrite is a preservative, the ingestion of foods containing an excessive amount of this substance can also cause acute intoxication up to death.

  2. Jul 15, 2023 · Very high levels of sodium nitrite can kill you. Sodium nitrite can also harm you if you inhale it or if it’s soaked up through your skin. It can irritate your eyes, skin, nose, and...

  3. The mechanism by which sodium nitrite causes death is methemoglobinemia. The oftentimes severe methemoglobinemia found in sodium nitrite poisoning cases results in systemic hypoxia, metabolic acidosis, and cyanosis. The reported signs of sodium nitrite poisoning are as follows:

  4. Feb 1, 2024 · Documented cases of sodium nitrite toxicity are almost exclusively caused by accidental ingestion; however, self-poisoning with sodium nitrite represents an increasing trend in nitrate-related deaths. This systematic review summarizes the most crucial evidence regarding the fatal toxicity of sodium nitrite.

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