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  1. The cheapest way to get from Santa Maria to San Diego costs only $57, and the quickest way takes just 5 hours. Find the travel option that best suits you.

    • Closest City Or Town to Halfway Point
    • Major City Closest to Halfway Point
    • Major Cities Along The Route

    The closest town to the halfway point is Hidden Hills, CA, situated 148 miles from San Diego, CA and 145 miles from Santa Maria, CA. It would take 2 hours 27 mins to go from San Diego to Hidden Hills and 2 hours 19 minsto go from Santa Maria to Hidden Hills.

    The major city closest to the halfway point between San Diego, CA and Santa Maria, CA is Los Angeles, CA, situated 121 miles from San Diego, CA and 170 miles from Santa Maria, CA. It would take 1 hour 58 mins to go from San Diego to and 2 hours 44 minsto go from Santa Maria to Los Angeles.

    Some other major cities along the route include Carlsbad, CA,Oceanside, CA,Irvine, CA,Santa Ana, CA,Orange, CA,Garden Grove, CA,Anaheim, CA,Fullerton, CA,Norwalk, CA,Downey, CA,East Los Angeles, CA,Glendale, CA,Burbank, CA,Thousand Oaks, CA,Oxnard, CA, and Ventura, CA.

  2. There are 243.33 miles from Santa Maria to San Diego in southeast direction and 290 miles (466.71 kilometers) by car, following the US-101 S route. Santa Maria and San Diego are 4 hours 39 mins far apart, if you drive non-stop . This is the fastest route from Santa Maria, CA to San Diego, CA . The halfway point is Hidden Hills, CA.

  3. The direct drive from San Diego to Santa Maria is 280 mi (451 km), and should have a drive time of 4 hrs 44 mins in normal traffic.

  4. Get a quick answer: It's 282 miles or 454 km from San Diego to Santa Maria (California), which takes about 4 hours, 32 minutes to drive.

  5. Driving distance from San Diego, CA to Santa Maria, CA. The total driving distance from San Diego, CA to Santa Maria, CA is 282 miles or 454 kilometers. Your trip begins in San Diego, California. It ends in Santa Maria, California.

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