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   Is it a pain or a itch?

   • Itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different.

   Itch - Wikipedia

   en.wikipedia.org/wiki/Itch

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   What is the relationship between itch and pain?

   • The relationship between itch and pain is best understood as antagonistic. Recordings of STT pruriceptive neurons showed that after being stimulated by histamine (itch/pruritic stimuli) the neuronal firing decreased when the skin was scratched. However, the same neuron increased firing after scratching in response to capsaicin.

   The Relationship Between Itch and Pain in Itch Pathways

   aggietranscript.ucdavis.edu/the-relationship-between-itch-and-pain-in-itch-pathways/

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   Is itch a subset of pain?

   • Given observations on the overlaps between itch and pain, itch was first theorized to be a subset of pain in the intensity model. This postulates that polymodal neurons (sensitive to many modalities) differentiate between itch and pain through patterns of firing or “intensity” due to weak or strong stimulation [1, 4, 6, 10].

   The Relationship Between Itch and Pain in Itch Pathways

   aggietranscript.ucdavis.edu/the-relationship-between-itch-and-pain-in-itch-pathways/

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2. www.scientificamerican.com › article › an-itch-notAn Itch Is Not a Low-Level Form of Pain | Scientific American

   www.scientificamerican.com › article › an-itch-not

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   May 23, 2013 · Once thought to be a low-level form of pain, itch is instead a distinct sensation with a dedicated neural circuit linking cells in the periphery of the body to the brain, a study in mice...

3. www.ncbi.nlm.nih.gov › pmc › articlesNew insights into the mechanisms of itch: are pain and itch ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Itch was considered as a sub-modality of pain, because two sensations share many similarities ( Box 1 ). Like acute pain, acute itch is protective and serves as a warning signal for potential tissue damage caused by invader such as parasite [ 126 ]. However, chronic itch leads to sleep disruption and severe skin lesions [ 75 ].

   • Author: Tong Liu, Ru-Rong Ji
   • DOI: 10.1007/s00424-013-1284-2

   • Publish Year: 2013
   • Published: 2013/12

4. en.wikipedia.org › wiki › ItchItch - Wikipedia

   en.wikipedia.org › wiki › Itch

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   Itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. [1] . Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different.

5. journals.physiology.org › doi › fullPhysiology and Pathophysiology of Itch | Physiological Reviews

   journals.physiology.org › doi › full

   Itch is a disease, not only a symptom of disease. Scratching an itch can be intensely pleasurable, yet chronic itch is a disease that impacts quality of life to the same extent as pain.

   • Author: Ferda Cevikbas, Ethan A. Lerner

   • Publish Year: 2020

6. aggietranscript.ucdavis.edu › the-relationshipThe Relationship Between Itch and Pain in Itch Pathways

   aggietranscript.ucdavis.edu › the-relationship

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   Itch is a somatosensory sensation, relying on the nervous system for detection and perception, therefore similar to other somatosensory sensations such as heat, touch, vibration, and most importantly, pain. Pain and itch have an antagonistic relationship, meaning each sensation has an opposing effect on the other.

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8. www.ncbi.nlm.nih.gov › pmc › articlesUnderstanding the pathophysiology of itch - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Itch is the dominant symptom of a vast variety of diseases from cutaneous inflammatory conditions such as atopic dermatitis to systemic, neurologic, and autoimmune disorders such as hepatic or renal failure, multiple sclerosis, or celiac disease.

9. news.berkeley.edu › 2011/05/02 › pain-and-itchPain and itch connected down deep | Berkeley

   news.berkeley.edu › 2011/05/02 › pain-and-itch

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   May 2, 2011 · Pain and itch are extremes of our sense of touch, which itself is not well understood, Bautista said. While research has shown in detail how touch receptors on the skin map to the brain, “it’s really an open question which molecules are involved in detecting tactile stimuli, like vibrations or light touch, and how these molecules are modulated.”