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- The biological-physiological aspects of aging include both the basic biological factors that underlie aging and the general health status. Since the probability of death increases rapidly with advancing age, it is clear that changes must occur in the individual which make him or her more and more vulnerable to disease.
www.britannica.com › science › human-agingHuman aging | Description, Physical Effects, & Psychological ...
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What are the biological-physiological aspects of aging?
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Jan 4, 2023 · Biologically speaking, aging—or senescence, which more accurately depicts the processes occurring from a biological standpoint—is a chronic, normal culmination of the loss of specific regenerative and bioprotective mechanisms that occur over time in an organism.
- A synopsis on aging—Theories, mechanisms and future prospects
Here, we summarize the main views of the different models of...
- Biological and Functional Biomarkers of Aging: Definition ...
Clinical and Biological Aging Phenotypes. The aging...
- A synopsis on aging—Theories, mechanisms and future prospects
- Overview
- Cardiovascular system
human aging, physiological changes that take place in the human body leading to senescence, the decline of biological functions and of the ability to adapt to metabolic stress. In humans the physiological developments are normally accompanied by psychological and behavioral changes, and other changes, involving social and economic factors, also occur.
Aging begins as soon as adulthood is reached and is as much a part of human life as are infancy, childhood, and adolescence. Gerontology (the study of aging) is concerned primarily with the changes that occur between the attainment of maturity and the death of the individual. The goal of research in gerontology is to identify the factors that influence these changes. Application of this knowledge can reduce the severity of some disabilities commonly associated with aging.
The biological-physiological aspects of aging include both the basic biological factors that underlie aging and the general health status. Since the probability of death increases rapidly with advancing age, it is clear that changes must occur in the individual which make him or her more and more vulnerable to disease. For example, a young adult may rapidly recover from pneumonia, whereas an elderly person may die.
Physiologists have found that the performance of many organs such as the heart, kidneys, brain, or lungs shows a gradual decline over the life span. Part of this decline is due to a loss of cells from these organs, with resultant reduction in the reserve capacities of the individual. Furthermore, the cells remaining in the elderly individual may not perform as well as those in the young. Certain cellular enzymes may be less active, and thus more time may be required to carry out chemical reactions. Ultimately the cell may die.
Britannica Quiz
Characteristics of the Human Body
Diseases of the heart are the single largest cause of death after age 65. Thus, with increasing age, the heart becomes more vulnerable to cardiovascular disease. Even in the absence of detectable disease, the heart undergoes deleterious changes with advancing age. Structural changes include a gradual loss of muscle fibres with an infiltration of adipose tissue (fat) and connective tissue. There is a gradual accumulation of insoluble granular material (lipofuscin, or “age pigment”) in cardiac muscle fibres. These granules, composed of proteins and lipids, make their first appearance by age 20 and increase gradually, so that by age 80 they may occupy as much as 5–10 percent of the volume of a muscle fibre.
The heart also shows a gradual reduction in performance with advancing age. The amount of blood pumped by the heart diminishes by about 50 percent between ages 20 and 90 years. There are marked individual differences in the effects of age. For example, some 80-year-old individuals may have cardiac function that is as good as that of the average 40-year-old individual.
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Under resting conditions, the heart rate does not change significantly with age. During each beat, however, the muscle fibres of the heart do not contract as rapidly in the old as in the young. This reduction in power, or rate of work, is due to the age-associated reduction in the activities of certain cellular enzymes that produce the energy required for muscular contraction.
In spite of these changes, the heart, in the absence of disease, is able to meet the demands placed upon it. In response to physical exercise, it can increase its rate to double or triple the amount of blood pumped each minute, although the maximum possible output falls, and the reserve capacity of the heart diminishes with age.
Describe any four biological changes associated with aging. List any three steps that individuals can try to undertake to achieve successful aging. Our society, like many of the others discussed earlier, has a mixed view of aging and older people.
The Biology of Aging. Nothing has been demonstrated to slow or reverse the primary aging process in humans; instead, the factors that are known to affect longevity do so by their influence on disease development, which is a part of secondary aging.
- John O. Holloszy
- 2000
Here, we summarize the main views of the different models of senescence, with a special emphasis on the biochemical processes that accompany aging. Though inherently complex, aging is characterized by numerous changes that take place at different levels of the biological hierarchy.
- João Pinto da Costa, Rui Vitorino, Gustavo M. Silva, Christine Vogel, Armando C. Duarte, Teresa Roch...
- 10.1016/j.arr.2016.06.005
- 2016
- 2016/08
Aug 22, 2020 · Clinical and Biological Aging Phenotypes. The aging phenotype can be described as a complex mosaic resulting from the interaction of a variety of environmental, stochastic, and genetic–epigenetic events/stimuli impinging lifelong on our body [4, 5].
May 24, 2024 · aging, progressive physiological changes in an organism that lead to senescence, or a decline of biological functions and of the organism’s ability to adapt to metabolic stress. Aging takes place in a cell, an organ, or the total organism with the passage of time. It is a process that goes on over the entire adult life span of any living thing.
