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Description. Provider of real estate agent services catering to all our clients throughout Annandale, Eskdale and the Scottish Borders.
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One to three days before a rash develops, you may show early signs of Stevens-Johnson syndrome, including:
•Fever
•A sore mouth and throat
•Fatigue
•Burning eyes
As the condition develops, other signs and symptoms include:
Stevens-Johnson syndrome requires immediate medical attention. Seek emergency medical care if you experience signs and symptoms of this condition. Drug-induced reactions may occur during the use of a medication or up to two weeks after discontinuing it.
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Stevens-Johnson syndrome is a rare and unpredictable illness. Your health care provider may not be able to identify its exact cause, but usually the condition is triggered by medication, an infection or both. You may react to medication while you're using it or up to two weeks after you've stopped using it.
Drugs that can cause Stevens-Johnson syndrome include:
•Anti-gout medications, such as allopurinol
•Medications to treat seizures and mental illness (anticonvulsants and antipsychotics)
•Antibacterial sulfonamides (including sulfasalazine)
•Nevirapine (Viramune, Viramune XR)
Factors that increase your risk of developing Stevens-Johnson syndrome include:
•An HIV infection. Among people with HIV, the incidence of Stevens-Johnson syndrome is about 100 times greater than among the general population.
•A weakened immune system. The immune system can be affected by an organ transplant, HIV/AIDS and autoimmune diseases.
•Cancer. People with cancer, particularly blood cancer, are at increased risk of Stevens-Johnson syndrome.
•A history of Stevens-Johnson syndrome. If you've had a medication-related form of this condition, you are at risk of a recurrence if you use that drug again.
•A family history of Stevens-Johnson syndrome. If an immediate blood relative has had Stevens-Johnson syndrome, you may be at increased risk of getting it too.
Stevens-Johnson syndrome complications include:
•Dehydration. Areas where the skin has shed lose fluids. And sores in the mouth and throat can make fluid intake difficult, resulting in dehydration.
•Blood infection (sepsis). Sepsis occurs when bacteria from an infection enter the bloodstream and spread throughout the body. Sepsis is a rapidly progressing, life-threatening condition that can cause shock and organ failure.
•Eye problems. The rash caused by Stevens-Johnson syndrome can lead to eye inflammation, dry eye and light sensitivity. In severe cases, it can lead to visual impairment and, rarely, blindness.
•Lung involvement. The condition may lead to an emergency situation in which the lungs can't get enough oxygen into the blood (acute respiratory failure).
•Permanent skin damage. When your skin grows back following Stevens-Johnson syndrome, it may have bumps and unusual coloring (dyspigmentation). And you may have scars. Lasting skin problems may cause your hair to fall out, and your fingernails and toenails may not grow as well as they did before.
•Consider genetic testing before taking certain drugs. The U.S. Food and Drug Administration recommends screening people of Asian and South Asian ancestry for a gene variation called HLA-B*1502 before starting treatment.
•If you've had this condition, avoid the medication that triggered it. If you've had Stevens-Johnson syndrome and your health care provider told you it was caused by a medication, avoid that drug and others like it. This is key to preventing a recurrence, which is usually more severe than the first episode and can be fatal.
Your immediate blood relatives also might want to avoid this drug because sometimes this condition runs in families.
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By Mayo Clinic Staff
Jan 07, 2023
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute, serious, and potentially fatal skin reaction in which there are sheet-like skin and mucosal loss.
Oct 4, 2022 · Legal and estate agency firm Cullen Kilshaw, which already has offices in seven towns in the Scottish Borders, has established a presence in Dumfries & Galloway by merging with Langholm practice Stevenson & Johnstone.
Stevens-Johnson syndrome (SJS) is a disorder that causes painful blisters and lesions on the skin and mucous membranes and can cause severe eye problems. Who is at risk of developing Stevens-Johnson syndrome? Some groups of people are at a higher risk of getting Stevens-Johnson syndrome, including:
Dec 18, 2020 · What is Stevens-Johnson syndrome (SJS)? Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious skin conditions that cause your skin to develop rashes, blisters, and then peel. Your mucus membranes, including your eyes, genitalia and mouth, are also affected.
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Stevens–Johnson syndrome ( SJS) is a type of severe skin reaction. [1] Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN) overlap, they are considered febrile mucocutaneous drug reactions and probably part of the same spectrum of disease, with SJS being less severe.
